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Structure and Role of BCOR PUFD in Noncanonical PRC1 Assembly and Disease.
Wong SJ, Senkovich O, Artigas JA, Gearhart MD, Ilangovan U, Graham DW, Abel KN, Yu T, Hinck AP, Bardwell VJ, Kim CA. Wong SJ, et al. Among authors: bardwell vj. Biochemistry. 2020 Jul 28;59(29):2718-2728. doi: 10.1021/acs.biochem.0c00285. Epub 2020 Jul 10. Biochemistry. 2020. PMID: 32628469 Free PMC article.
BCOR regulates myeloid cell proliferation and differentiation.
Cao Q, Gearhart MD, Gery S, Shojaee S, Yang H, Sun H, Lin DC, Bai JW, Mead M, Zhao Z, Chen Q, Chien WW, Alkan S, Alpermann T, Haferlach T, Müschen M, Bardwell VJ, Koeffler HP. Cao Q, et al. Among authors: bardwell vj. Leukemia. 2016 May;30(5):1155-65. doi: 10.1038/leu.2016.2. Epub 2016 Feb 5. Leukemia. 2016. PMID: 26847029 Free PMC article.
A Non-canonical BCOR-PRC1.1 Complex Represses Differentiation Programs in Human ESCs.
Wang Z, Gearhart MD, Lee YW, Kumar I, Ramazanov B, Zhang Y, Hernandez C, Lu AY, Neuenkirchen N, Deng J, Jin J, Kluger Y, Neubert TA, Bardwell VJ, Ivanova NB. Wang Z, et al. Among authors: bardwell vj. Cell Stem Cell. 2018 Feb 1;22(2):235-251.e9. doi: 10.1016/j.stem.2017.12.002. Epub 2018 Jan 11. Cell Stem Cell. 2018. PMID: 29337181 Free PMC article.
Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis.
Kelly MJ, So J, Rogers AJ, Gregory G, Li J, Zethoven M, Gearhart MD, Bardwell VJ, Johnstone RW, Vervoort SJ, Kats LM. Kelly MJ, et al. Among authors: bardwell vj. Nat Commun. 2019 Mar 22;10(1):1347. doi: 10.1038/s41467-019-09250-6. Nat Commun. 2019. PMID: 30902969 Free PMC article.
Loss of function mutations of BCOR in classical Hodgkin lymphoma.
Giefing M, Gearhart MD, Schneider M, Overbeck B, Klapper W, Hartmann S, Ustaszewski A, Weniger MA, Wiehle L, Hansmann ML, Melnick A, Béguelin W, Sundström C, Küppers R, Bardwell VJ, Siebert R. Giefing M, et al. Among authors: bardwell vj. Leuk Lymphoma. 2022 May;63(5):1080-1090. doi: 10.1080/10428194.2021.2015587. Epub 2021 Dec 27. Leuk Lymphoma. 2022. PMID: 34957890
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.
Béguelin W, Teater M, Gearhart MD, Calvo Fernández MT, Goldstein RL, Cárdenas MG, Hatzi K, Rosen M, Shen H, Corcoran CM, Hamline MY, Gascoyne RD, Levine RL, Abdel-Wahab O, Licht JD, Shaknovich R, Elemento O, Bardwell VJ, Melnick AM. Béguelin W, et al. Among authors: bardwell vj. Cancer Cell. 2016 Aug 8;30(2):197-213. doi: 10.1016/j.ccell.2016.07.006. Cancer Cell. 2016. PMID: 27505670 Free PMC article.
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