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PCSK9 deficiency rewires heart metabolism and drives heart failure with preserved ejection fraction.
Da Dalt L, Castiglioni L, Baragetti A, Audano M, Svecla M, Bonacina F, Pedretti S, Uboldi P, Benzoni P, Giannetti F, Barbuti A, Pellegatta F, Indino S, Donetti E, Sironi L, Mitro N, Catapano AL, Norata GD. Da Dalt L, et al. Among authors: barbuti a. Eur Heart J. 2021 Aug 21;42(32):3078-3090. doi: 10.1093/eurheartj/ehab431. Eur Heart J. 2021. PMID: 34252181 Free PMC article.
Generation of the induced human pluripotent stem cell lines CSSi009-A from a patient with a GNB5 pathogenic variant, and CSSi010-A from a CRISPR/Cas9 engineered GNB5 knock-out human cell line.
Malerba N, Benzoni P, Squeo GM, Milanesi R, Giannetti F, Sadleir LG, Poke G, Augello B, Croce AI, Barbuti A, Merla G. Malerba N, et al. Among authors: barbuti a. Stem Cell Res. 2019 Oct;40:101547. doi: 10.1016/j.scr.2019.101547. Epub 2019 Aug 22. Stem Cell Res. 2019. PMID: 31479876 Free article.
A detailed characterization of the hyperpolarization-activated "funny" current (If) in human-induced pluripotent stem cell (iPSC)-derived cardiomyocytes with pacemaker activity.
Giannetti F, Benzoni P, Campostrini G, Milanesi R, Bucchi A, Baruscotti M, Dell'Era P, Rossini A, Barbuti A. Giannetti F, et al. Among authors: barbuti a. Pflugers Arch. 2021 Jul;473(7):1009-1021. doi: 10.1007/s00424-021-02571-w. Epub 2021 May 2. Pflugers Arch. 2021. PMID: 33934225 Free PMC article.
Dual role of miR-1 in the development and function of sinoatrial cells.
Benzoni P, Nava L, Giannetti F, Guerini G, Gualdoni A, Bazzini C, Milanesi R, Bucchi A, Baruscotti M, Barbuti A. Benzoni P, et al. Among authors: barbuti a. J Mol Cell Cardiol. 2021 Aug;157:104-112. doi: 10.1016/j.yjmcc.2021.05.001. Epub 2021 May 6. J Mol Cell Cardiol. 2021. PMID: 33964276 Free article.
PITX2 gain-of-function mutation associated with atrial fibrillation alters mitochondrial activity in human iPSC atrial-like cardiomyocytes.
Benzoni P, Da Dalt L, Elia N, Popolizio V, Cospito A, Giannetti F, Dell'Era P, Olesen MS, Bucchi A, Baruscotti M, Norata GD, Barbuti A. Benzoni P, et al. Among authors: barbuti a. Front Physiol. 2023 Nov 13;14:1250951. doi: 10.3389/fphys.2023.1250951. eCollection 2023. Front Physiol. 2023. PMID: 38028792 Free PMC article.
A gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity is associated with familial Inappropriate Sinus Tachycardia.
Baruscotti M, Bucchi A, Milanesi R, Paina M, Barbuti A, Gnecchi-Ruscone T, Bianco E, Vitali-Serdoz L, Cappato R, DiFrancesco D. Baruscotti M, et al. Among authors: barbuti a. Eur Heart J. 2017 Jan 21;38(4):280-288. doi: 10.1093/eurheartj/ehv582. Eur Heart J. 2017. PMID: 28182231 No abstract available.
79 results