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The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.
Vervoort SJ, Welsh SA, Devlin JR, Barbieri E, Knight DA, Offley S, Bjelosevic S, Costacurta M, Todorovski I, Kearney CJ, Sandow JJ, Fan Z, Blyth B, McLeod V, Vissers JHA, Pavic K, Martin BP, Gregory G, Demosthenous E, Zethoven M, Kong IY, Hawkins ED, Hogg SJ, Kelly MJ, Newbold A, Simpson KJ, Kauko O, Harvey KF, Ohlmeyer M, Westermarck J, Gray N, Gardini A, Johnstone RW. Vervoort SJ, et al. Among authors: barbieri e. Cell. 2021 Jun 10;184(12):3143-3162.e32. doi: 10.1016/j.cell.2021.04.022. Epub 2021 May 17. Cell. 2021. PMID: 34004147 Free PMC article.
Targeted Enhancer Activation by a Subunit of the Integrator Complex.
Barbieri E, Trizzino M, Welsh SA, Owens TA, Calabretta B, Carroll M, Sarma K, Gardini A. Barbieri E, et al. Mol Cell. 2018 Jul 5;71(1):103-116.e7. doi: 10.1016/j.molcel.2018.05.031. Epub 2018 Jun 28. Mol Cell. 2018. PMID: 30008316 Free PMC article.
Rapid and Scalable Profiling of Nascent RNA with fastGRO.
Barbieri E, Hill C, Quesnel-Vallières M, Zucco AJ, Barash Y, Gardini A. Barbieri E, et al. Cell Rep. 2020 Nov 10;33(6):108373. doi: 10.1016/j.celrep.2020.108373. Cell Rep. 2020. PMID: 33176136 Free PMC article.
EGR1 is a gatekeeper of inflammatory enhancers in human macrophages.
Trizzino M, Zucco A, Deliard S, Wang F, Barbieri E, Veglia F, Gabrilovich D, Gardini A. Trizzino M, et al. Among authors: barbieri e. Sci Adv. 2021 Jan 13;7(3):eaaz8836. doi: 10.1126/sciadv.aaz8836. Print 2021 Jan. Sci Adv. 2021. PMID: 33523892 Free PMC article.
Deletion of a pseudogene within a fragile site triggers the oncogenic expression of the mitotic CCSER1 gene.
Santoliquido BM, Frenquelli M, Contadini C, Bestetti S, Gaviraghi M, Barbieri E, De Antoni A, Albarello L, Amabile A, Gardini A, Lombardo A, Doglioni C, Provero P, Soddu S, Cittaro D, Tonon G. Santoliquido BM, et al. Among authors: barbieri e. Life Sci Alliance. 2021 Jun 29;4(8):e202101019. doi: 10.26508/lsa.202101019. Print 2021 Aug. Life Sci Alliance. 2021. PMID: 34187875 Free PMC article.
Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression.
Porazzi P, Petruk S, Pagliaroli L, De Dominici M, Deming D 2nd, Puccetti MV, Kushinsky S, Kumar G, Minieri V, Barbieri E, Deliard S, Grande A, Trizzino M, Gardini A, Canaani E, Palmisiano N, Porcu P, Ertel A, Fortina P, Eischen CM, Mazo A, Calabretta B. Porazzi P, et al. Among authors: barbieri e. Cancer Res. 2022 Feb 1;82(3):458-471. doi: 10.1158/0008-5472.CAN-21-1297. Epub 2021 Dec 13. Cancer Res. 2022. PMID: 34903608 Free PMC article.
Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling.
Pascolutti R, Algisi V, Conte A, Raimondi A, Pasham M, Upadhyayula S, Gaudin R, Maritzen T, Barbieri E, Caldieri G, Tordonato C, Confalonieri S, Freddi S, Malabarba MG, Maspero E, Polo S, Tacchetti C, Haucke V, Kirchhausen T, Di Fiore PP, Sigismund S. Pascolutti R, et al. Among authors: barbieri e. Cell Rep. 2019 Jun 4;27(10):3049-3061.e6. doi: 10.1016/j.celrep.2019.05.017. Cell Rep. 2019. PMID: 31167147 Free PMC article.
686 results