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Liver Immune Cells Release Type 1 Interferon Due to DNA Sensing and Amplify Liver Injury from Acetaminophen Overdose.
Araujo AM, Antunes MM, Mattos MS, Diniz AB, Alvarenga DM, Nakagaki BN, Carvalho É, Lacerda VAS, Carvalho-Gontijo R, Goulart J, Mafra K, Freitas-Lopes MA, Oliveira HMC, Dutra CM, David BA, Mendes Silva A, Quesniaux V, Ryffel B, Oliveira SC, Barber GN, Mansur DS, Cunha TM, Rezende RM, Oliveira AG, Menezes GB. Araujo AM, et al. Among authors: barber gn. Cells. 2018 Jul 27;7(8):88. doi: 10.3390/cells7080088. Cells. 2018. PMID: 30060463 Free PMC article.
Brucella abortus Triggers a cGAS-Independent STING Pathway To Induce Host Protection That Involves Guanylate-Binding Proteins and Inflammasome Activation.
Costa Franco MM, Marim F, Guimarães ES, Assis NRG, Cerqueira DM, Alves-Silva J, Harms J, Splitter G, Smith J, Kanneganti TD, de Queiroz NMGP, Gutman D, Barber GN, Oliveira SC. Costa Franco MM, et al. Among authors: barber gn. J Immunol. 2018 Jan 15;200(2):607-622. doi: 10.4049/jimmunol.1700725. Epub 2017 Dec 4. J Immunol. 2018. PMID: 29203515 Free PMC article.
Brucella suppress STING expression via miR-24 to enhance infection.
Khan M, Harms JS, Liu Y, Eickhoff J, Tan JW, Hu T, Cai F, Guimaraes E, Oliveira SC, Dahl R, Cheng Y, Gutman D, Barber GN, Splitter GA, Smith JA. Khan M, et al. Among authors: barber gn. PLoS Pathog. 2020 Oct 27;16(10):e1009020. doi: 10.1371/journal.ppat.1009020. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33108406 Free PMC article.
The cytosolic sensor STING is required for intestinal homeostasis and control of inflammation.
Canesso MCC, Lemos L, Neves TC, Marim FM, Castro TBR, Veloso ÉS, Queiroz CP, Ahn J, Santiago HC, Martins FS, Alves-Silva J, Ferreira E, Cara DC, Vieira AT, Barber GN, Oliveira SC, Faria AMC. Canesso MCC, et al. Among authors: barber gn. Mucosal Immunol. 2018 May;11(3):820-834. doi: 10.1038/mi.2017.88. Epub 2017 Dec 20. Mucosal Immunol. 2018. PMID: 29346345 Free article.
Cytoplasmic DNA innate immune pathways.
Barber GN. Barber GN. Immunol Rev. 2011 Sep;243(1):99-108. doi: 10.1111/j.1600-065X.2011.01051.x. Immunol Rev. 2011. PMID: 21884170 Review.
191 results