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Targeting STING oligomerization with small-molecule inhibitors.
Humphries F, Shmuel-Galia L, Jiang Z, Zhou JY, Barasa L, Mondal S, Wilson R, Sultana N, Shaffer SA, Ng SL, Pesiridis GS, Thompson PR, Fitzgerald KA. Humphries F, et al. Among authors: barasa l. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2305420120. doi: 10.1073/pnas.2305420120. Epub 2023 Aug 7. Proc Natl Acad Sci U S A. 2023. PMID: 37549268 Free PMC article.
Development of LB244, an Irreversible STING Antagonist.
Barasa L, Chaudhuri S, Zhou JY, Jiang Z, Choudhary S, Green RM, Wiggin E, Cameron M, Humphries F, Fitzgerald KA, Thompson PR. Barasa L, et al. J Am Chem Soc. 2023 Sep 20;145(37):20273-20288. doi: 10.1021/jacs.3c03637. Epub 2023 Sep 11. J Am Chem Soc. 2023. PMID: 37695732
Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors.
Pasquero S, Gugliesi F, Biolatti M, Dell'Oste V, Albano C, Bajetto G, Griffante G, Trifirò L, Brugo B, Raviola S, Lacarbonara D, Yang Q, Sudeshna S, Barasa L, Haniff H, Thompson PR, Landolfo S, De Andrea M. Pasquero S, et al. Among authors: barasa l. PLoS Pathog. 2023 Dec 6;19(12):e1011849. doi: 10.1371/journal.ppat.1011849. eCollection 2023 Dec. PLoS Pathog. 2023. PMID: 38055760 Free PMC article.
17 results