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188 results

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Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia.
Stuani L, Sabatier M, Saland E, Cognet G, Poupin N, Bosc C, Castelli FA, Gales L, Turtoi E, Montersino C, Farge T, Boet E, Broin N, Larrue C, Baran N, Cissé MY, Conti M, Loric S, Kaoma T, Hucteau A, Zavoriti A, Sahal A, Mouchel PL, Gotanègre M, Cassan C, Fernando L, Wang F, Hosseini M, Chu-Van E, Le Cam L, Carroll M, Selak MA, Vey N, Castellano R, Fenaille F, Turtoi A, Cazals G, Bories P, Gibon Y, Nicolay B, Ronseaux S, Marszalek JR, Takahashi K, DiNardo CD, Konopleva M, Pancaldi V, Collette Y, Bellvert F, Jourdan F, Linares LK, Récher C, Portais JC, Sarry JE. Stuani L, et al. Among authors: baran n. J Exp Med. 2021 May 3;218(5):e20200924. doi: 10.1084/jem.20200924. J Exp Med. 2021. PMID: 33760042 Free PMC article.
Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes.
Matre P, Velez J, Jacamo R, Qi Y, Su X, Cai T, Chan SM, Lodi A, Sweeney SR, Ma H, Davis RE, Baran N, Haferlach T, Su X, Flores ER, Gonzalez D, Konoplev S, Samudio I, DiNardo C, Majeti R, Schimmer AD, Li W, Wang T, Tiziani S, Konopleva M. Matre P, et al. Among authors: baran n. Oncotarget. 2016 Nov 29;7(48):79722-79735. doi: 10.18632/oncotarget.12944. Oncotarget. 2016. PMID: 27806325 Free PMC article.
Assessing Metabolic Intervention with a Glutaminase Inhibitor in Real-Time by Hyperpolarized Magnetic Resonance in Acute Myeloid Leukemia.
Zacharias NM, Baran N, Shanmugavelandy SS, Lee J, Lujan JV, Dutta P, Millward SW, Cai T, Wood CG, Piwnica-Worms D, Konopleva M, Bhattacharya PK. Zacharias NM, et al. Among authors: baran n. Mol Cancer Ther. 2019 Nov;18(11):1937-1946. doi: 10.1158/1535-7163.MCT-18-0985. Epub 2019 Aug 6. Mol Cancer Ther. 2019. PMID: 31387889 Free PMC article.
Inhibition of Oxidative Phosphorylation Reverses Bone Marrow Hypoxia Visualized in Imageable Syngeneic B-ALL Mouse Model.
Rytelewski M, Harutyunyan K, Baran N, Mallampati S, Zal MA, Cavazos A, Butler JM, Konoplev S, El Khatib M, Plunkett S, Marszalek JR, Andreeff M, Zal T, Konopleva M. Rytelewski M, et al. Among authors: baran n. Front Oncol. 2020 Jun 30;10:991. doi: 10.3389/fonc.2020.00991. eCollection 2020. Front Oncol. 2020. PMID: 32695673 Free PMC article.
SYK inhibition targets acute myeloid leukemia stem cells by blocking their oxidative metabolism.
Polak A, Bialopiotrowicz E, Krzymieniewska B, Wozniak J, Stojak M, Cybulska M, Kaniuga E, Mikula M, Jablonska E, Gorniak P, Noyszewska-Kania M, Szydlowski M, Piechna K, Piwocka K, Bugajski L, Lech-Maranda E, Barankiewicz J, Kolkowska-Lesniak A, Patkowska E, Glodkowska-Mrowka E, Baran N, Juszczynski P. Polak A, et al. Among authors: baran n. Cell Death Dis. 2020 Nov 6;11(11):956. doi: 10.1038/s41419-020-03156-8. Cell Death Dis. 2020. PMID: 33159047 Free PMC article.
Overexpression of CD200 is a Stem Cell-Specific Mechanism of Immune Evasion in AML.
Herbrich S, Baran N, Cai T, Weng C, Aitken MJL, Post SM, Henderson J, Shi C, Richard-Carpentier G, Sauvageau G, Baggerly K, Al-Atrash G, Davis RE, Daver N, Zha D, Konopleva M. Herbrich S, et al. Among authors: baran n. J Immunother Cancer. 2021 Jul;9(7):e002968. doi: 10.1136/jitc-2021-002968. J Immunother Cancer. 2021. PMID: 34326171 Free PMC article.
Exogenous mitochondrial transfer and endogenous mitochondrial fission facilitate AML resistance to OxPhos inhibition.
Saito K, Zhang Q, Yang H, Yamatani K, Ai T, Ruvolo V, Baran N, Cai T, Ma H, Jacamo R, Kuruvilla V, Imoto J, Kinjo S, Ikeo K, Moriya K, Suzuki K, Miida T, Kim YM, Vellano CP, Andreeff M, Marszalek JR, Tabe Y, Konopleva M. Saito K, et al. Among authors: baran n. Blood Adv. 2021 Oct 26;5(20):4233-4255. doi: 10.1182/bloodadvances.2020003661. Blood Adv. 2021. PMID: 34507353 Free PMC article.
188 results