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A systems approach points to a therapeutic role for retinoids in asparaginase-associated pancreatitis.
Tsai CY, Saito T, Sarangdhar M, Abu-El-Haija M, Wen L, Lee B, Yu M, Lipata DA, Manohar M, Barakat MT, Contrepois K, Tran TH, Theoret Y, Bo N, Ding Y, Stevenson K, Ladas EJ, Silverman LB, Quadro L, Anthony TG, Jegga AG, Husain SZ. Tsai CY, et al. Among authors: barakat mt. Sci Transl Med. 2023 Mar 15;15(687):eabn2110. doi: 10.1126/scitranslmed.abn2110. Epub 2023 Mar 15. Sci Transl Med. 2023. PMID: 36921036 Free PMC article.
The Protective Effects of Calcineurin on Pancreatitis in Mice Depend on the Cellular Source.
Wen L, Javed TA, Dobbs AK, Brown R, Niu M, Li L, Khalid A, Barakat MT, Xiao X, Yimlamai D, Konnikova L, Yu M, Byersdorfer CA, Husain SZ. Wen L, et al. Among authors: barakat mt. Gastroenterology. 2020 Sep;159(3):1036-1050.e8. doi: 10.1053/j.gastro.2020.05.051. Epub 2020 May 20. Gastroenterology. 2020. PMID: 32445858 Free PMC article.
Rectal INdomethacin, oral TacROlimus, or their combination for the prevention of post-ERCP pancreatitis (INTRO Trial): Protocol for a randomized, controlled, double-blinded trial.
Akshintala VS, Husain SZ, Brenner TA, Singh A, Singh VK, Khashab MA, Sperna Weiland CJ, van Geenen EJM, Bush N, Barakat M, Srivastava A, Kochhar R, Talukdar R, Rodge G, Wu CCH, Lakhtakia S, Sinha SK, Goenka MK, Reddy DN. Akshintala VS, et al. Pancreatology. 2022 Nov;22(7):887-893. doi: 10.1016/j.pan.2022.07.008. Epub 2022 Jul 19. Pancreatology. 2022. PMID: 35872074
Clinical insights into drug-associated pancreatic injury.
Barakat MT, Abu-El-Haija M, Husain SZ. Barakat MT, et al. Curr Opin Gastroenterol. 2022 Sep 1;38(5):482-486. doi: 10.1097/MOG.0000000000000865. Curr Opin Gastroenterol. 2022. PMID: 35916322 Review.
Preclinical safety evaluation of calcineurin inhibitors delivered through an intraductal route to prevent post-ERCP pancreatitis demonstrates endocrine and systemic safety.
Ni J, Khalid A, Lin YC, Barakat MT, Wang J, Tsai CY, Azar PRS, Ding Y, Murayi JA, Jayaraman T, Poropatich R, Bottino R, Wen L, Papachristou GI, Swaminathan G, Yu M, Husain SZ. Ni J, et al. Among authors: barakat mt. Pancreatology. 2023 Jun;23(4):333-340. doi: 10.1016/j.pan.2023.03.009. Epub 2023 Mar 30. Pancreatology. 2023. PMID: 37031049
Rectal administration of tacrolimus protects against post-ERCP pancreatitis in mice.
Lin YC, Ni J, Swaminathan G, Khalid A, Barakat MT, Frymoyer AR, Tsai CY, Ding Y, Murayi JA, Jayaraman T, Poropatich R, Bottino R, Wen L, Papachristou GI, Sheth SG, Yu M, Husain SZ. Lin YC, et al. Among authors: barakat mt. Pancreatology. 2023 Nov;23(7):777-783. doi: 10.1016/j.pan.2023.09.080. Epub 2023 Sep 24. Pancreatology. 2023. PMID: 37778935
122 results