Lithium targeting of AMPK protects against cisplatin-induced acute kidney injury by enhancing autophagy in renal proximal tubular epithelial cells.
Bao H, Zhang Q, Liu X, Song Y, Li X, Wang Z, Li C, Peng A, Gong R.
Bao H, et al.
FASEB J. 2019 Dec;33(12):14370-14381. doi: 10.1096/fj.201901712R. Epub 2019 Oct 29.
FASEB J. 2019.
PMID: 31661633
Our findings suggest that lithium represents a promising therapeutic strategy for protecting renal tubular cells against cisplatin-induced AKI by enhancing autophagy via AMPK-alpha activation.-Bao, H., Zhang, Q., Liu, X., Song, Y., Li, X., Wang, Z., Li, C., Peng, A. …
Our findings suggest that lithium represents a promising therapeutic strategy for protecting renal tubular cells against cisplatin-induced A …