Balsells J - Search Results

1

Synthesis of bis-macrocyclic HCV protease inhibitor MK-6325 via intramolecular sp²-sp³ Suzuki-Miyaura coupling and ring closing metathesis.

Li H, Scott JP, Chen CY, Journet M, Belyk K, Balsells J, Kosjek B, Baxter CA, Stewart GW, Wise C, Alam M, Song ZJ, Tan L. Li H, et al. Among authors: balsells j. Org Lett. 2015 Mar 20;17(6):1533-6. doi: 10.1021/acs.orglett.5b00418. Epub 2015 Mar 10. Org Lett. 2015. PMID: 25754231

2

Synthesis of a CGRP Receptor Antagonist via an Asymmetric Synthesis of 3-Fluoro-4-aminopiperidine.

Molinaro C, Phillips EM, Xiang B, Milczek E, Shevlin M, Balsells J, Ceglia S, Chen J, Chen L, Chen Q, Fei Z, Hoerrner S, Qi J, de Lera Ruiz M, Tan L, Wan B, Yin J. Molinaro C, et al. Among authors: balsells j. J Org Chem. 2019 Jun 21;84(12):8006-8018. doi: 10.1021/acs.joc.9b00569. Epub 2019 Jun 5. J Org Chem. 2019. PMID: 31124362

3

Synthesis of [1,2,4]triazolo[4,3-alpha]piperazines via highly reactive chloromethyloxadiazoles.

Balsells J, Dimichele L, Liu J, Kubryk M, Hansen K, Armstrong JD 3rd. Balsells J, et al. Org Lett. 2005 Mar 17;7(6):1039-42. doi: 10.1021/ol0474406. Org Lett. 2005. PMID: 15760133

4

An efficient catalyst for Pd-catalyzed carbonylation of aryl arenesulfonates.

Cai C, Rivera NR, Balsells J, Sidler RR, McWilliams JC, Shultz CS, Sun Y. Cai C, et al. Among authors: balsells j. Org Lett. 2006 Oct 26;8(22):5161-4. doi: 10.1021/ol062208g. Org Lett. 2006. PMID: 17048868

5

Synthesis of 4-Alkylated Isocoumarins via Pd-Catalyzed α-Arylation Reaction.

Plunkett S, DeRatt LG, Kuduk SD, Balsells J. Plunkett S, et al. Among authors: balsells j. Org Lett. 2020 Oct 2;22(19):7662-7666. doi: 10.1021/acs.orglett.0c02851. Epub 2020 Sep 24. Org Lett. 2020. PMID: 32969657

6

Toward the total synthesis of variecolin.

Molander GA, Quirmbach MS, Silva LF Jr, Spencer KC, Balsells J. Molander GA, et al. Among authors: balsells j. Org Lett. 2001 Jul 26;3(15):2257-60. doi: 10.1021/ol015763l. Org Lett. 2001. PMID: 11463290

7

Optimization of asymmetric catalysts using achiral ligands: metal geometry-induced ligand asymmetry.

Davis TJ, Balsells J, Carroll PJ, Walsh PJ. Davis TJ, et al. Among authors: balsells j. Org Lett. 2001 Jul 12;3(14):2161-4. doi: 10.1021/ol016003d. Org Lett. 2001. PMID: 11440569

8

Copper-Catalyzed Synthesis of 5-Carboxyl-4-perfluoroalkyl Triazoles.

Panish R, Thieu T, Balsells J. Panish R, et al. Among authors: balsells j. Org Lett. 2021 Aug 6;23(15):5937-5941. doi: 10.1021/acs.orglett.1c02037. Epub 2021 Jul 21. Org Lett. 2021. PMID: 34286985

9

Mineralocorticoid receptor antagonists: identification of heterocyclic amide replacements in the oxazolidinedione series.

Cox JM, Chu HD, Yang C, Shen HC, Wu Z, Balsells J, Crespo A, Brown P, Zamlynny B, Wiltsie J, Clemas J, Gibson J, Contino L, Lisnock J, Zhou G, Garcia-Calvo M, Bateman T, Xu L, Tong X, Crook M, Sinclair P. Cox JM, et al. Among authors: balsells j. Bioorg Med Chem Lett. 2014 Apr 1;24(7):1681-4. doi: 10.1016/j.bmcl.2014.02.057. Epub 2014 Mar 1. Bioorg Med Chem Lett. 2014. PMID: 24630411

10

Discovery of novel oxazolidinedione derivatives as potent and selective mineralocorticoid receptor antagonists.

Yang C, Shen HC, Wu Z, Chu HD, Cox JM, Balsells J, Crespo A, Brown P, Zamlynny B, Wiltsie J, Clemas J, Gibson J, Contino L, Lisnock J, Zhou G, Garcia-Calvo M, Bateman T, Xu L, Tong X, Crook M, Sinclair P. Yang C, et al. Among authors: balsells j. Bioorg Med Chem Lett. 2013 Aug 1;23(15):4388-92. doi: 10.1016/j.bmcl.2013.05.077. Epub 2013 Jun 4. Bioorg Med Chem Lett. 2013. PMID: 23777778

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