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Signaling Modulation via Minimal C-Terminal Modifications of Apelin-13.
Théroux L, Van Den Hauwe R, Trân K, Fournier J, Desgagné M, Meneboo N, Lavallée A, Fröhlich U, Côté J, Hollanders C, Longpré JM, Murza A, Marsault E, Sarret P, Boudreault PL, Ballet S. Théroux L, et al. Among authors: ballet s. ACS Pharmacol Transl Sci. 2023 Jan 26;6(2):290-305. doi: 10.1021/acsptsci.2c00219. eCollection 2023 Feb 10. ACS Pharmacol Transl Sci. 2023. PMID: 36798478 Free PMC article.
χ-Space Screening of Dermorphin-Based Tetrapeptides through Use of Constrained Arylazepinone and Quinolinone Scaffolds.
Van der Poorten O, Van Den Hauwe R, Eiselt E, Betti C, Guillemyn K, Chung NN, Hallé F, Bihel F, Schiller PW, Tourwé D, Sarret P, Gendron L, Ballet S. Van der Poorten O, et al. Among authors: ballet s. ACS Med Chem Lett. 2017 Oct 4;8(11):1177-1182. doi: 10.1021/acsmedchemlett.7b00347. eCollection 2017 Nov 9. ACS Med Chem Lett. 2017. PMID: 29152051 Free PMC article.
Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings.
Willemse T, Eiselt E, Hollanders K, Schepens W, van Vlijmen HWT, Chung NN, Blais V, Holleran B, Longpré JM, Schiller PW, Maes BUW, Sarret P, Gendron L, Ballet S. Willemse T, et al. Among authors: ballet s. Bioorg Med Chem Lett. 2018 Jul 15;28(13):2320-2323. doi: 10.1016/j.bmcl.2018.05.015. Epub 2018 May 12. Bioorg Med Chem Lett. 2018. PMID: 29853330 Free PMC article.
Corrigendum to "Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings" [Bioorg. Med. Chem. Lett. 28(13) (2018) 2320-2323].
Willemse T, Eiselt E, Hollanders K, Schepens W, van Vlijmen HWT, Chung NN, Blais V, Holleran B, Longpré JM, Schiller PW, Maes BUW, Sarret P, Gendron L, Ballet S. Willemse T, et al. Among authors: ballet s. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3418. doi: 10.1016/j.bmcl.2018.08.023. Epub 2018 Sep 5. Bioorg Med Chem Lett. 2018. PMID: 30195888 No abstract available.
Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia.
Eiselt E, Gonzalez S, Martin C, Chartier M, Betti C, Longpré JM, Cavelier F, Tourwé D, Gendron L, Ballet S, Sarret P. Eiselt E, et al. Among authors: ballet s. ACS Chem Neurosci. 2019 Nov 20;10(11):4535-4544. doi: 10.1021/acschemneuro.9b00390. Epub 2019 Oct 21. ACS Chem Neurosci. 2019. PMID: 31589400
Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists.
Claff T, Yu J, Blais V, Patel N, Martin C, Wu L, Han GW, Holleran BJ, Van der Poorten O, White KL, Hanson MA, Sarret P, Gendron L, Cherezov V, Katritch V, Ballet S, Liu ZJ, Müller CE, Stevens RC. Claff T, et al. Among authors: ballet s. Sci Adv. 2019 Nov 27;5(11):eaax9115. doi: 10.1126/sciadv.aax9115. eCollection 2019 Nov. Sci Adv. 2019. PMID: 31807708 Free PMC article.
Optimized Opioid-Neurotensin Multitarget Peptides: From Design to Structure-Activity Relationship Studies.
Gonzalez S, Dumitrascuta M, Eiselt E, Louis S, Kunze L, Blasiol A, Vivancos M, Previti S, Dewolf E, Martin C, Tourwé D, Cavelier F, Gendron L, Sarret P, Spetea M, Ballet S. Gonzalez S, et al. Among authors: ballet s. J Med Chem. 2020 Nov 12;63(21):12929-12941. doi: 10.1021/acs.jmedchem.0c01376. Epub 2020 Sep 23. J Med Chem. 2020. PMID: 32902268 Free PMC article.
Structure-Based Design of Melanocortin 4 Receptor Ligands Based on the SHU-9119-hMC4R Cocrystal Structure†.
Martin C, Gimenez LE, Williams SY, Jing Y, Wu Y, Hollanders C, Van der Poorten O, Gonzalez S, Van Holsbeeck K, Previti S, Lamouroux A, Zhao S, Tourwé D, Stevens RC, Cone RD, Ballet S. Martin C, et al. Among authors: ballet s. J Med Chem. 2021 Jan 14;64(1):357-369. doi: 10.1021/acs.jmedchem.0c01620. Epub 2020 Nov 14. J Med Chem. 2021. PMID: 33190475
176 results