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Loss of function of transcription factor EB remodels lipid metabolism and cell death pathways in the cardiomyocyte.
Trivedi PC, Bartlett JJ, Mercer A, Slade L, Surette M, Ballabio A, Flibotte S, Hussein B, Rodrigues B, Kienesberger PC, Pulinilkunnil T. Trivedi PC, et al. Among authors: ballabio a. Biochim Biophys Acta Mol Basis Dis. 2020 Oct 1;1866(10):165832. doi: 10.1016/j.bbadis.2020.165832. Epub 2020 May 8. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 32437957 Free article.
A gene network regulating lysosomal biogenesis and function.
Sardiello M, Palmieri M, di Ronza A, Medina DL, Valenza M, Gennarino VA, Di Malta C, Donaudy F, Embrione V, Polishchuk RS, Banfi S, Parenti G, Cattaneo E, Ballabio A. Sardiello M, et al. Among authors: ballabio a. Science. 2009 Jul 24;325(5939):473-7. doi: 10.1126/science.1174447. Epub 2009 Jun 25. Science. 2009. PMID: 19556463
Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease.
Spampanato C, Feeney E, Li L, Cardone M, Lim JA, Annunziata F, Zare H, Polishchuk R, Puertollano R, Parenti G, Ballabio A, Raben N. Spampanato C, et al. Among authors: ballabio a. EMBO Mol Med. 2013 May;5(5):691-706. doi: 10.1002/emmm.201202176. Epub 2013 Apr 18. EMBO Mol Med. 2013. PMID: 23606558 Free PMC article.
Transcription Factor EB Controls Metabolic Flexibility during Exercise.
Mansueto G, Armani A, Viscomi C, D'Orsi L, De Cegli R, Polishchuk EV, Lamperti C, Di Meo I, Romanello V, Marchet S, Saha PK, Zong H, Blaauw B, Solagna F, Tezze C, Grumati P, Bonaldo P, Pessin JE, Zeviani M, Sandri M, Ballabio A. Mansueto G, et al. Among authors: ballabio a. Cell Metab. 2017 Jan 10;25(1):182-196. doi: 10.1016/j.cmet.2016.11.003. Epub 2016 Dec 20. Cell Metab. 2017. PMID: 28011087 Free PMC article.
Lysosomal disorders: from storage to cellular damage.
Ballabio A, Gieselmann V. Ballabio A, et al. Biochim Biophys Acta. 2009 Apr;1793(4):684-96. doi: 10.1016/j.bbamcr.2008.12.001. Epub 2008 Dec 8. Biochim Biophys Acta. 2009. PMID: 19111581 Free article. Review.
TFEB links autophagy to lysosomal biogenesis.
Settembre C, Di Malta C, Polito VA, Garcia Arencibia M, Vetrini F, Erdin S, Erdin SU, Huynh T, Medina D, Colella P, Sardiello M, Rubinsztein DC, Ballabio A. Settembre C, et al. Among authors: ballabio a. Science. 2011 Jun 17;332(6036):1429-33. doi: 10.1126/science.1204592. Epub 2011 May 26. Science. 2011. PMID: 21617040 Free PMC article.
454 results