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Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-D-ribose 2'-oxidase.
Landge S, Mullick AB, Nagalapur K, Neres J, Subbulakshmi V, Murugan K, Ghosh A, Sadler C, Fellows MD, Humnabadkar V, Mahadevaswamy J, Vachaspati P, Sharma S, Kaur P, Mallya M, Rudrapatna S, Awasthy D, Sambandamurthy VK, Pojer F, Cole ST, Balganesh TS, Ugarkar BG, Balasubramanian V, Bandodkar BS, Panda M, Ramachandran V. Landge S, et al. Among authors: balganesh ts. Bioorg Med Chem. 2015 Dec 15;23(24):7694-710. doi: 10.1016/j.bmc.2015.11.017. Epub 2015 Nov 18. Bioorg Med Chem. 2015. PMID: 26643218
Aminopyrazinamides: novel and specific GyrB inhibitors that kill replicating and nonreplicating Mycobacterium tuberculosis.
Shirude PS, Madhavapeddi P, Tucker JA, Murugan K, Patil V, Basavarajappa H, Raichurkar AV, Humnabadkar V, Hussein S, Sharma S, Ramya VK, Narayan CB, Balganesh TS, Sambandamurthy VK. Shirude PS, et al. Among authors: balganesh ts. ACS Chem Biol. 2013 Mar 15;8(3):519-23. doi: 10.1021/cb300510w. Epub 2012 Dec 31. ACS Chem Biol. 2013. PMID: 23268609
Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity.
Landge S, Ramachandran V, Kumar A, Neres J, Murugan K, Sadler C, Fellows MD, Humnabadkar V, Vachaspati P, Raichurkar A, Sharma S, Ravishankar S, Guptha S, Sambandamurthy VK, Balganesh TS, Ugarkar BG, Balasubramanian V, Bandodkar BS, Panda M. Landge S, et al. Among authors: balganesh ts. ChemMedChem. 2016 Feb 4;11(3):331-9. doi: 10.1002/cmdc.201500462. Epub 2016 Jan 11. ChemMedChem. 2016. PMID: 26751718
Rising standards for tuberculosis drug development.
Balganesh TS, Alzari PM, Cole ST. Balganesh TS, et al. Trends Pharmacol Sci. 2008 Nov;29(11):576-81. doi: 10.1016/j.tips.2008.08.001. Epub 2008 Sep 15. Trends Pharmacol Sci. 2008. PMID: 18799223 Review.
Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis.
Makarov V, Manina G, Mikusova K, Möllmann U, Ryabova O, Saint-Joanis B, Dhar N, Pasca MR, Buroni S, Lucarelli AP, Milano A, De Rossi E, Belanova M, Bobovska A, Dianiskova P, Kordulakova J, Sala C, Fullam E, Schneider P, McKinney JD, Brodin P, Christophe T, Waddell S, Butcher P, Albrethsen J, Rosenkrands I, Brosch R, Nandi V, Bharath S, Gaonkar S, Shandil RK, Balasubramanian V, Balganesh T, Tyagi S, Grosset J, Riccardi G, Cole ST. Makarov V, et al. Science. 2009 May 8;324(5928):801-4. doi: 10.1126/science.1171583. Epub 2009 Mar 19. Science. 2009. PMID: 19299584 Free PMC article.
Exploring the potential of adjunct therapy in tuberculosis.
Rayasam GV, Balganesh TS. Rayasam GV, et al. Among authors: balganesh ts. Trends Pharmacol Sci. 2015 Aug;36(8):506-13. doi: 10.1016/j.tips.2015.05.005. Epub 2015 Jun 11. Trends Pharmacol Sci. 2015. PMID: 26073420 Review.
Study of the interaction between bacteriophage T4 asiA and Escherichia coli sigma(70), using the yeast two-hybrid system: neutralization of asiA toxicity to E. coli cells by coexpression of a truncated sigma(70) fragment.
Sharma UK, Ravishankar S, Shandil RK, Praveen PV, Balganesh TS. Sharma UK, et al. Among authors: balganesh ts. J Bacteriol. 1999 Sep;181(18):5855-9. doi: 10.1128/JB.181.18.5855-5859.1999. J Bacteriol. 1999. PMID: 10482532 Free PMC article.
Biomedicine and biotechnology: public health impact.
Ganguly NK, Croft S, Singh L, Sinha S, Balganesh T. Ganguly NK, et al. Biomed Res Int. 2014;2014:524785. doi: 10.1155/2014/524785. Epub 2014 Apr 8. Biomed Res Int. 2014. PMID: 24809051 Free PMC article. No abstract available.
31 results