Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

17 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling.
Bosakova M, Abraham SP, Nita A, Hruba E, Buchtova M, Taylor SP, Duran I, Martin J, Svozilova K, Barta T, Varecha M, Balek L, Kohoutek J, Radaszkiewicz T, Pusapati GV, Bryja V, Rush ET, Thiffault I, Nickerson DA, Bamshad MJ; University of Washington Center for Mendelian Genomics; Rohatgi R, Cohn DH, Krakow D, Krejci P. Bosakova M, et al. Among authors: balek l. EMBO Mol Med. 2020 Nov 6;12(11):e11739. doi: 10.15252/emmm.201911739. Epub 2020 Oct 14. EMBO Mol Med. 2020. PMID: 33200460 Free PMC article.
An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.
Paige Taylor S, Kunova Bosakova M, Varecha M, Balek L, Barta T, Trantirek L, Jelinkova I, Duran I, Vesela I, Forlenza KN, Martin JH, Hampl A; University of Washington Center for Mendelian Genomics; Bamshad M, Nickerson D, Jaworski ML, Song J, Ko HW, Cohn DH, Krakow D, Krejci P. Paige Taylor S, et al. Among authors: balek l. Hum Mol Genet. 2016 Sep 15;25(18):3998-4011. doi: 10.1093/hmg/ddw240. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466187 Free PMC article.
Fibroblast growth factor and canonical WNT/β-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage.
Buchtova M, Oralova V, Aklian A, Masek J, Vesela I, Ouyang Z, Obadalova T, Konecna Z, Spoustova T, Pospisilova T, Matula P, Varecha M, Balek L, Gudernova I, Jelinkova I, Duran I, Cervenkova I, Murakami S, Kozubik A, Dvorak P, Bryja V, Krejci P. Buchtova M, et al. Among authors: balek l. Biochim Biophys Acta. 2015 May;1852(5):839-50. doi: 10.1016/j.bbadis.2014.12.020. Epub 2015 Jan 2. Biochim Biophys Acta. 2015. PMID: 25558817 Free article.
The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases.
Fafilek B, Balek L, Bosakova MK, Varecha M, Nita A, Gregor T, Gudernova I, Krenova J, Ghosh S, Piskacek M, Jonatova L, Cernohorsky NH, Zieba JT, Kostas M, Haugsten EM, Wesche J, Erneux C, Trantirek L, Krakow D, Krejci P. Fafilek B, et al. Among authors: balek l. Sci Signal. 2018 Sep 18;11(548):eaap8608. doi: 10.1126/scisignal.aap8608. Sci Signal. 2018. PMID: 30228226
Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase.
Kunova Bosakova M, Nita A, Gregor T, Varecha M, Gudernova I, Fafilek B, Barta T, Basheer N, Abraham SP, Balek L, Tomanova M, Fialova Kucerova J, Bosak J, Potesil D, Zieba J, Song J, Konik P, Park S, Duran I, Zdrahal Z, Smajs D, Jansen G, Fu Z, Ko HW, Hampl A, Trantirek L, Krakow D, Krejci P. Kunova Bosakova M, et al. Among authors: balek l. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4316-4325. doi: 10.1073/pnas.1800338116. Epub 2019 Feb 19. Proc Natl Acad Sci U S A. 2019. PMID: 30782830 Free PMC article.
ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3.
Balek L, Gudernova I, Vesela I, Hampl M, Oralova V, Kunova Bosakova M, Varecha M, Nemec P, Hall T, Abbadessa G, Hatch N, Buchtova M, Krejci P. Balek L, et al. Bone. 2017 Dec;105:57-66. doi: 10.1016/j.bone.2017.08.016. Epub 2017 Aug 18. Bone. 2017. PMID: 28826843
Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct β-catenin phosphorylation.
Krejci P, Aklian A, Kaucka M, Sevcikova E, Prochazkova J, Masek JK, Mikolka P, Pospisilova T, Spoustova T, Weis M, Paznekas WA, Wolf JH, Gutkind JS, Wilcox WR, Kozubik A, Jabs EW, Bryja V, Salazar L, Vesela I, Balek L. Krejci P, et al. Among authors: balek l. PLoS One. 2012;7(4):e35826. doi: 10.1371/journal.pone.0035826. Epub 2012 Apr 27. PLoS One. 2012. PMID: 22558232 Free PMC article.
Statins do not inhibit the FGFR signaling in chondrocytes.
Fafilek B, Hampl M, Ricankova N, Vesela I, Balek L, Kunova Bosakova M, Gudernova I, Varecha M, Buchtova M, Krejci P. Fafilek B, et al. Among authors: balek l. Osteoarthritis Cartilage. 2017 Sep;25(9):1522-1530. doi: 10.1016/j.joca.2017.05.014. Epub 2017 Jun 3. Osteoarthritis Cartilage. 2017. PMID: 28583899 Free article.
Effect of FGFR inhibitors on chicken limb development.
Horakova D, Cela P, Krejci P, Balek L, Moravcova Balkova S, Matalova E, Buchtova M. Horakova D, et al. Among authors: balek l. Dev Growth Differ. 2014 Oct;56(8):555-72. doi: 10.1111/dgd.12156. Epub 2014 Oct 3. Dev Growth Differ. 2014. PMID: 25280231
17 results