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Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease.
Forner S, Kawauchi S, Balderrama-Gutierrez G, Kramár EA, Matheos DP, Phan J, Javonillo DI, Tran KM, Hingco E, da Cunha C, Rezaie N, Alcantara JA, Baglietto-Vargas D, Jansen C, Neumann J, Wood MA, MacGregor GR, Mortazavi A, Tenner AJ, LaFerla FM, Green KN. Forner S, et al. Among authors: balderrama gutierrez g. Sci Data. 2021 Oct 15;8(1):270. doi: 10.1038/s41597-021-01054-y. Sci Data. 2021. PMID: 34654824 Free PMC article.
Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
Baglietto-Vargas D, Forner S, Cai L, Martini AC, Trujillo-Estrada L, Swarup V, Nguyen MMT, Do Huynh K, Javonillo DI, Tran KM, Phan J, Jiang S, Kramár EA, Nuñez-Diaz C, Balderrama-Gutierrez G, Garcia F, Childs J, Rodriguez-Ortiz CJ, Garcia-Leon JA, Kitazawa M, Shahnawaz M, Matheos DP, Ma X, Da Cunha C, Walls KC, Ager RR, Soto C, Gutierrez A, Moreno-Gonzalez I, Mortazavi A, Tenner AJ, MacGregor GR, Wood M, Green KN, LaFerla FM. Baglietto-Vargas D, et al. Nat Commun. 2021 Apr 23;12(1):2421. doi: 10.1038/s41467-021-22624-z. Nat Commun. 2021. PMID: 33893290 Free PMC article.
C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer's disease.
Gomez-Arboledas A, Carvalho K, Balderrama-Gutierrez G, Chu SH, Liang HY, Schartz ND, Selvan P, Petrisko TJ, Pan MA, Mortazavi A, Tenner AJ. Gomez-Arboledas A, et al. Among authors: balderrama gutierrez g. Acta Neuropathol Commun. 2022 Aug 17;10(1):116. doi: 10.1186/s40478-022-01416-6. Acta Neuropathol Commun. 2022. PMID: 35978440 Free PMC article.
Modulation of C5a-C5aR1 signaling alters the dynamics of AD progression.
Carvalho K, Schartz ND, Balderrama-Gutierrez G, Liang HY, Chu SH, Selvan P, Gomez-Arboledas A, Petrisko TJ, Fonseca MI, Mortazavi A, Tenner AJ. Carvalho K, et al. Among authors: balderrama gutierrez g. J Neuroinflammation. 2022 Jul 11;19(1):178. doi: 10.1186/s12974-022-02539-2. J Neuroinflammation. 2022. PMID: 35820938 Free PMC article.
Identification of robust cellular programs using reproducible LDA that impact sex-specific disease progression in different genotypes of a mouse model of AD.
Rezaie N, Rebboah E, Williams BA, Liang HY, Reese F, Balderrama-Gutierrez G, Dionne LA, Reinholdt L, Trout D, Wold BJ, Mortazavi A. Rezaie N, et al. Among authors: balderrama gutierrez g. bioRxiv [Preprint]. 2024 Feb 29:2024.02.26.582178. doi: 10.1101/2024.02.26.582178. bioRxiv. 2024. PMID: 38464087 Free PMC article. Preprint.
Systematic assessment of long-read RNA-seq methods for transcript identification and quantification.
Pardo-Palacios FJ, Wang D, Reese F, Diekhans M, Carbonell-Sala S, Williams B, Loveland JE, De María M, Adams MS, Balderrama-Gutierrez G, Behera AK, Gonzalez JM, Hunt T, Lagarde J, Liang CE, Li H, Jerryd Meade M, Moraga Amador DA, Prjibelski AD, Birol I, Bostan H, Brooks AM, Hasan Çelik M, Chen Y, Du MRM, Felton C, Göke J, Hafezqorani S, Herwig R, Kawaji H, Lee J, Liang Li J, Lienhard M, Mikheenko A, Mulligan D, Ming Nip K, Pertea M, Ritchie ME, Sim AD, Tang AD, Kei Wan Y, Wang C, Wong BY, Yang C, Barnes I, Berry A, Capella S, Dhillon N, Fernandez-Gonzalez JM, Ferrández-Peral L, Garcia-Reyero N, Goetz S, Hernández-Ferrer C, Kondratova L, Liu T, Martinez-Martin A, Menor C, Mestre-Tomás J, Mudge JM, Panayotova NG, Paniagua A, Repchevsky D, Rouchka E, Saint-John B, Sapena E, Sheynkman L, Laird Smith M, Suner MM, Takahashi H, Youngworth IA, Carninci P, Denslow ND, Guigó R, Hunter ME, Tilgner HU, Wold BJ, Vollmers C, Frankish A, Fai Au K, Sheynkman GM, Mortazavi A, Conesa A, Brooks AN. Pardo-Palacios FJ, et al. Among authors: balderrama gutierrez g. bioRxiv [Preprint]. 2023 Jul 27:2023.07.25.550582. doi: 10.1101/2023.07.25.550582. bioRxiv. 2023. PMID: 37546854 Free PMC article. Preprint.
14 results