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Mechanism of baricitinib supports artificial intelligence-predicted testing in COVID-19 patients.
Stebbing J, Krishnan V, de Bono S, Ottaviani S, Casalini G, Richardson PJ, Monteil V, Lauschke VM, Mirazimi A, Youhanna S, Tan YJ, Baldanti F, Sarasini A, Terres JAR, Nickoloff BJ, Higgs RE, Rocha G, Byers NL, Schlichting DE, Nirula A, Cardoso A, Corbellino M; Sacco Baricitinib Study Group. Stebbing J, et al. Among authors: baldanti f. EMBO Mol Med. 2020 Aug 7;12(8):e12697. doi: 10.15252/emmm.202012697. Epub 2020 Jun 24. EMBO Mol Med. 2020. PMID: 32473600 Free PMC article.
A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate.
Baldanti F, Silini E, Sarasini A, Talarico CL, Stanat SC, Biron KK, Furione M, Bono F, Palù G, Gerna G. Baldanti F, et al. J Virol. 1995 Feb;69(2):796-800. doi: 10.1128/JVI.69.2.796-800.1995. J Virol. 1995. PMID: 7815545 Free PMC article.
We report the molecular and biochemical characterization of a HCMV ganciclovir-resistant strain (VR3480) previously recovered from a patient with AIDS who was undergoing multiple courses of ganciclovir treatment (G. Gerna, F. Baldanti, M. Zavattoni, A. Sarasini, E. …
We report the molecular and biochemical characterization of a HCMV ganciclovir-resistant strain (VR3480) previously recovered from a patient …
Effect of foscarnet induction treatment on quantitation of human cytomegalovirus (HCMV) DNA in peripheral blood polymorphonuclear leukocytes and aqueous humor of AIDS patients with HCMV retinitis. The Italian Foscarnet Study Group.
Gerna G, Baldanti F, Sarasini A, Furione M, Percivalle E, Revello MG, Zipeto D, Zella D. Gerna G, et al. Among authors: baldanti f. Antimicrob Agents Chemother. 1994 Jan;38(1):38-44. doi: 10.1128/AAC.38.1.38. Antimicrob Agents Chemother. 1994. PMID: 8141577 Free PMC article. Clinical Trial.
Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovered from patients with AIDS.
Baldanti F, Underwood MR, Stanat SC, Biron KK, Chou S, Sarasini A, Silini E, Gerna G. Baldanti F, et al. J Virol. 1996 Mar;70(3):1390-5. doi: 10.1128/JVI.70.3.1390-1395.1996. J Virol. 1996. PMID: 8627655 Free PMC article.
Three human cytomegalovirus (HCMV) strains (VR4760, VR4955, and VR5120) showing double resistance to ganciclovir (GCV) and foscarnet (PFA) were isolated from three patients with AIDS who underwent multiple sequential courses of therapy with GCV and PFA (A. Sarasini, F. …
Three human cytomegalovirus (HCMV) strains (VR4760, VR4955, and VR5120) showing double resistance to ganciclovir (GCV) and foscarnet (PFA) w …
537 results