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Proteolysis of mature HIV-1 p6 Gag protein by the insulin-degrading enzyme (IDE) regulates virus replication in an Env-dependent manner.
Hahn F, Schmalen A, Setz C, Friedrich M, Schlößer S, Kölle J, Spranger R, Rauch P, Fraedrich K, Reif T, Karius-Fischer J, Balasubramanyam A, Henklein P, Fossen T, Schubert U. Hahn F, et al. Among authors: balasubramanyam a. PLoS One. 2017 Apr 7;12(4):e0174254. doi: 10.1371/journal.pone.0174254. eCollection 2017. PLoS One. 2017. PMID: 28388673 Free PMC article. Clinical Trial.
Effects of transgenic expression of HIV-1 Vpr on lipid and energy metabolism in mice.
Balasubramanyam A, Mersmann H, Jahoor F, Phillips TM, Sekhar RV, Schubert U, Brar B, Iyer D, Smith EO, Takahashi H, Lu H, Anderson P, Kino T, Henklein P, Kopp JB. Balasubramanyam A, et al. Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E40-8. doi: 10.1152/ajpendo.00163.2006. Epub 2006 Aug 1. Am J Physiol Endocrinol Metab. 2007. PMID: 16882932 Free article.
HIV-1 Vpr induces adipose dysfunction in vivo through reciprocal effects on PPAR/GR co-regulation.
Agarwal N, Iyer D, Patel SG, Sekhar RV, Phillips TM, Schubert U, Oplt T, Buras ED, Samson SL, Couturier J, Lewis DE, Rodriguez-Barradas MC, Jahoor F, Kino T, Kopp JB, Balasubramanyam A. Agarwal N, et al. Among authors: balasubramanyam a. Sci Transl Med. 2013 Nov 27;5(213):213ra164. doi: 10.1126/scitranslmed.3007148. Sci Transl Med. 2013. PMID: 24285483 Free PMC article.
Adipocytes impair efficacy of antiretroviral therapy.
Couturier J, Winchester LC, Suliburk JW, Wilkerson GK, Podany AT, Agarwal N, Xuan Chua CY, Nehete PN, Nehete BP, Grattoni A, Sastry KJ, Fletcher CV, Lake JE, Balasubramanyam A, Lewis DE. Couturier J, et al. Among authors: balasubramanyam a. Antiviral Res. 2018 Jun;154:140-148. doi: 10.1016/j.antiviral.2018.04.002. Epub 2018 Apr 6. Antiviral Res. 2018. PMID: 29630975 Free PMC article.
Treatment of dyslipidemia in HIV-infected patients.
Sekhar RV, Balasubramanyam A. Sekhar RV, et al. Among authors: balasubramanyam a. Expert Opin Pharmacother. 2010 Aug;11(11):1845-54. doi: 10.1517/14656566.2010.487484. Expert Opin Pharmacother. 2010. PMID: 20486828 Review.
329 results