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Single-cell profiling of transcriptome and histone modifications with EpiDamID.
Rang FJ, de Luca KL, de Vries SS, Valdes-Quezada C, Boele E, Nguyen PD, Guerreiro I, Sato Y, Kimura H, Bakkers J, Kind J. Rang FJ, et al. Among authors: bakkers j. Mol Cell. 2022 May 19;82(10):1956-1970.e14. doi: 10.1016/j.molcel.2022.03.009. Epub 2022 Apr 1. Mol Cell. 2022. PMID: 35366395 Free PMC article.
Genome-wide RNA Tomography in the zebrafish embryo.
Junker JP, Noël ES, Guryev V, Peterson KA, Shah G, Huisken J, McMahon AP, Berezikov E, Bakkers J, van Oudenaarden A. Junker JP, et al. Among authors: bakkers j. Cell. 2014 Oct 23;159(3):662-75. doi: 10.1016/j.cell.2014.09.038. Cell. 2014. PMID: 25417113 Free article.
Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart.
Honkoop H, de Bakker DE, Aharonov A, Kruse F, Shakked A, Nguyen PD, de Heus C, Garric L, Muraro MJ, Shoffner A, Tessadori F, Peterson JC, Noort W, Bertozzi A, Weidinger G, Posthuma G, Grün D, van der Laarse WJ, Klumperman J, Jaspers RT, Poss KD, van Oudenaarden A, Tzahor E, Bakkers J. Honkoop H, et al. Among authors: bakkers j. Elife. 2019 Dec 23;8:e50163. doi: 10.7554/eLife.50163. Elife. 2019. PMID: 31868166 Free PMC article.
Macrophages provide a transient muscle stem cell niche via NAMPT secretion.
Ratnayake D, Nguyen PD, Rossello FJ, Wimmer VC, Tan JL, Galvis LA, Julier Z, Wood AJ, Boudier T, Isiaku AI, Berger S, Oorschot V, Sonntag C, Rogers KL, Marcelle C, Lieschke GJ, Martino MM, Bakkers J, Currie PD. Ratnayake D, et al. Among authors: bakkers j. Nature. 2021 Mar;591(7849):281-287. doi: 10.1038/s41586-021-03199-7. Epub 2021 Feb 10. Nature. 2021. PMID: 33568815
Cardiac regenerative capacity: an evolutionary afterthought?
Nguyen PD, de Bakker DEM, Bakkers J. Nguyen PD, et al. Among authors: bakkers j. Cell Mol Life Sci. 2021 Jun;78(12):5107-5122. doi: 10.1007/s00018-021-03831-9. Epub 2021 May 5. Cell Mol Life Sci. 2021. PMID: 33950316 Free PMC article. Review.
Live imaging of adult zebrafish cardiomyocyte proliferation ex vivo.
Honkoop H, Nguyen PD, van der Velden VEM, Sonnen KF, Bakkers J. Honkoop H, et al. Among authors: bakkers j. Development. 2021 Sep 15;148(18):dev199740. doi: 10.1242/dev.199740. Epub 2021 Sep 13. Development. 2021. PMID: 34397091 Free PMC article.
Recurrent de novo missense variants across multiple histone H4 genes underlie a neurodevelopmental syndrome.
Tessadori F, Duran K, Knapp K, Fellner M; Deciphering Developmental Disorders Study; Smithson S, Beleza Meireles A, Elting MW, Waisfisz Q, O'Donnell-Luria A, Nowak C, Douglas J, Ronan A, Brunet T, Kotzaeridou U, Svihovec S, Saenz MS, Thiffault I, Del Viso F, Devine P, Rego S, Tenney J, van Haeringen A, Ruivenkamp CAL, Koene S, Robertson SP, Deshpande C, Pfundt R, Verbeek N, van de Kamp JM, Weiss JMM, Ruiz A, Gabau E, Banne E, Pepler A, Bottani A, Laurent S, Guipponi M, Bijlsma E, Bruel AL, Sorlin A, Willis M, Powis Z, Smol T, Vincent-Delorme C, Baralle D, Colin E, Revencu N, Calpena E, Wilkie AOM, Chopra M, Cormier-Daire V, Keren B, Afenjar A, Niceta M, Terracciano A, Specchio N, Tartaglia M, Rio M, Barcia G, Rondeau S, Colson C, Bakkers J, Mace PD, Bicknell LS, van Haaften G. Tessadori F, et al. Among authors: bakkers j. Am J Hum Genet. 2022 Apr 7;109(4):750-758. doi: 10.1016/j.ajhg.2022.02.003. Epub 2022 Feb 23. Am J Hum Genet. 2022. PMID: 35202563 Free PMC article.
Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration.
Nguyen PD, Gooijers I, Campostrini G, Verkerk AO, Honkoop H, Bouwman M, de Bakker DEM, Koopmans T, Vink A, Lamers GEM, Shakked A, Mars J, Mulder AA, Chocron S, Bartscherer K, Tzahor E, Mummery CL, de Boer TP, Bellin M, Bakkers J. Nguyen PD, et al. Among authors: bakkers j. Science. 2023 May 19;380(6646):758-764. doi: 10.1126/science.abo6718. Epub 2023 May 18. Science. 2023. PMID: 37200435
Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischemic injury.
Shakked A, Petrover Z, Aharonov A, Ghiringhelli M, Umansky KB, Kain D, Elkahal J, Divinsky Y, Nguyen PD, Miyara S, Friedlander G, Savidor A, Zhang L, Perez DE, Sarig R, Lendengolts D, Bueno-Levy H, Kastan N, Levin Y, Bakkers J, Gepstein L, Tzahor E. Shakked A, et al. Among authors: bakkers j. Nat Cardiovasc Res. 2023 Apr;2(4):383-398. doi: 10.1038/s44161-023-00250-w. Epub 2023 Mar 8. Nat Cardiovasc Res. 2023. PMID: 37974970 Free PMC article.
149 results