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Macrophages provide a transient muscle stem cell niche via NAMPT secretion.
Ratnayake D, Nguyen PD, Rossello FJ, Wimmer VC, Tan JL, Galvis LA, Julier Z, Wood AJ, Boudier T, Isiaku AI, Berger S, Oorschot V, Sonntag C, Rogers KL, Marcelle C, Lieschke GJ, Martino MM, Bakkers J, Currie PD. Ratnayake D, et al. Among authors: bakkers j. Nature. 2021 Mar;591(7849):281-287. doi: 10.1038/s41586-021-03199-7. Epub 2021 Feb 10. Nature. 2021. PMID: 33568815
Cardiac regenerative capacity: an evolutionary afterthought?
Nguyen PD, de Bakker DEM, Bakkers J. Nguyen PD, et al. Among authors: bakkers j. Cell Mol Life Sci. 2021 Jun;78(12):5107-5122. doi: 10.1007/s00018-021-03831-9. Epub 2021 May 5. Cell Mol Life Sci. 2021. PMID: 33950316 Free PMC article. Review.
Live imaging of adult zebrafish cardiomyocyte proliferation ex vivo.
Honkoop H, Nguyen PD, van der Velden VEM, Sonnen KF, Bakkers J. Honkoop H, et al. Among authors: bakkers j. Development. 2021 Sep 15;148(18):dev199740. doi: 10.1242/dev.199740. Epub 2021 Sep 13. Development. 2021. PMID: 34397091 Free PMC article.
Single-cell profiling of transcriptome and histone modifications with EpiDamID.
Rang FJ, de Luca KL, de Vries SS, Valdes-Quezada C, Boele E, Nguyen PD, Guerreiro I, Sato Y, Kimura H, Bakkers J, Kind J. Rang FJ, et al. Among authors: bakkers j. Mol Cell. 2022 May 19;82(10):1956-1970.e14. doi: 10.1016/j.molcel.2022.03.009. Epub 2022 Apr 1. Mol Cell. 2022. PMID: 35366395 Free PMC article.
Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration.
Nguyen PD, Gooijers I, Campostrini G, Verkerk AO, Honkoop H, Bouwman M, de Bakker DEM, Koopmans T, Vink A, Lamers GEM, Shakked A, Mars J, Mulder AA, Chocron S, Bartscherer K, Tzahor E, Mummery CL, de Boer TP, Bellin M, Bakkers J. Nguyen PD, et al. Among authors: bakkers j. Science. 2023 May 19;380(6646):758-764. doi: 10.1126/science.abo6718. Epub 2023 May 18. Science. 2023. PMID: 37200435
Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischemic injury.
Shakked A, Petrover Z, Aharonov A, Ghiringhelli M, Umansky KB, Kain D, Elkahal J, Divinsky Y, Nguyen PD, Miyara S, Friedlander G, Savidor A, Zhang L, Perez DE, Sarig R, Lendengolts D, Bueno-Levy H, Kastan N, Levin Y, Bakkers J, Gepstein L, Tzahor E. Shakked A, et al. Among authors: bakkers j. Nat Cardiovasc Res. 2023 Apr;2(4):383-398. doi: 10.1038/s44161-023-00250-w. Epub 2023 Mar 8. Nat Cardiovasc Res. 2023. PMID: 37974970 Free PMC article.
Mutations in SGOL1 cause a novel cohesinopathy affecting heart and gut rhythm.
Chetaille P, Preuss C, Burkhard S, Côté JM, Houde C, Castilloux J, Piché J, Gosset N, Leclerc S, Wünnemann F, Thibeault M, Gagnon C, Galli A, Tuck E, Hickson GR, El Amine N, Boufaied I, Lemyre E, de Santa Barbara P, Faure S, Jonzon A, Cameron M, Dietz HC, Gallo-McFarlane E, Benson DW, Moreau C, Labuda D; FORGE Canada Consortium; Zhan SH, Shen Y, Jomphe M, Jones SJ, Bakkers J, Andelfinger G. Chetaille P, et al. Among authors: bakkers j. Nat Genet. 2014 Nov;46(11):1245-9. doi: 10.1038/ng.3113. Epub 2014 Oct 5. Nat Genet. 2014. PMID: 25282101
Germline mutations affecting the histone H4 core cause a developmental syndrome by altering DNA damage response and cell cycle control.
Tessadori F, Giltay JC, Hurst JA, Massink MP, Duran K, Vos HR, van Es RM; Deciphering Developmental Disorders Study; Scott RH, van Gassen KLI, Bakkers J, van Haaften G. Tessadori F, et al. Among authors: bakkers j. Nat Genet. 2017 Nov;49(11):1642-1646. doi: 10.1038/ng.3956. Epub 2017 Sep 18. Nat Genet. 2017. PMID: 28920961
149 results