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Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins.
Hazenbos WL, Kajihara KK, Vandlen R, Morisaki JH, Lehar SM, Kwakkenbos MJ, Beaumont T, Bakker AQ, Phung Q, Swem LR, Ramakrishnan S, Kim J, Xu M, Shah IM, Diep BA, Sai T, Sebrell A, Khalfin Y, Oh A, Koth C, Lin SJ, Lee BC, Strandh M, Koefoed K, Andersen PS, Spits H, Brown EJ, Tan MW, Mariathasan S. Hazenbos WL, et al. Among authors: bakker aq. PLoS Pathog. 2013;9(10):e1003653. doi: 10.1371/journal.ppat.1003653. Epub 2013 Oct 10. PLoS Pathog. 2013. PMID: 24130480 Free PMC article. Clinical Trial.
Hepatitis C virus Broadly Neutralizing Monoclonal Antibodies Isolated 25 Years after Spontaneous Clearance.
Merat SJ, Molenkamp R, Wagner K, Koekkoek SM, van de Berg D, Yasuda E, Böhne M, Claassen YB, Grady BP, Prins M, Bakker AQ, de Jong MD, Spits H, Schinkel J, Beaumont T. Merat SJ, et al. Among authors: bakker aq. PLoS One. 2016 Oct 24;11(10):e0165047. doi: 10.1371/journal.pone.0165047. eCollection 2016. PLoS One. 2016. PMID: 27776169 Free PMC article.
Bispecific antibody generated with sortase and click chemistry has broad antiinfluenza virus activity.
Wagner K, Kwakkenbos MJ, Claassen YB, Maijoor K, Böhne M, van der Sluijs KF, Witte MD, van Zoelen DJ, Cornelissen LA, Beaumont T, Bakker AQ, Ploegh HL, Spits H. Wagner K, et al. Among authors: bakker aq. Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16820-5. doi: 10.1073/pnas.1408605111. Epub 2014 Nov 10. Proc Natl Acad Sci U S A. 2014. PMID: 25385586 Free PMC article.
Establishment of Systems to Enable Isolation of Porcine Monoclonal Antibodies Broadly Neutralizing the Porcine Reproductive and Respiratory Syndrome Virus.
Goldeck D, Perry DM, Hayes JWP, Johnson LPM, Young JE, Roychoudhury P, McLuskey EL, Moffat K, Bakker AQ, Kwakkenbos MJ, Frossard JP, Rowland RRR, Murtaugh MP, Graham SP. Goldeck D, et al. Among authors: bakker aq. Front Immunol. 2019 Mar 27;10:572. doi: 10.3389/fimmu.2019.00572. eCollection 2019. Front Immunol. 2019. PMID: 30972067 Free PMC article.
Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
McLellan JS, Chen M, Joyce MG, Sastry M, Stewart-Jones GB, Yang Y, Zhang B, Chen L, Srivatsan S, Zheng A, Zhou T, Graepel KW, Kumar A, Moin S, Boyington JC, Chuang GY, Soto C, Baxa U, Bakker AQ, Spits H, Beaumont T, Zheng Z, Xia N, Ko SY, Todd JP, Rao S, Graham BS, Kwong PD. McLellan JS, et al. Among authors: bakker aq. Science. 2013 Nov 1;342(6158):592-8. doi: 10.1126/science.1243283. Science. 2013. PMID: 24179220 Free PMC article.
A common solution to group 2 influenza virus neutralization.
Friesen RH, Lee PS, Stoop EJ, Hoffman RM, Ekiert DC, Bhabha G, Yu W, Juraszek J, Koudstaal W, Jongeneelen M, Korse HJ, Ophorst C, Brinkman-van der Linden EC, Throsby M, Kwakkenbos MJ, Bakker AQ, Beaumont T, Spits H, Kwaks T, Vogels R, Ward AB, Goudsmit J, Wilson IA. Friesen RH, et al. Among authors: bakker aq. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):445-50. doi: 10.1073/pnas.1319058110. Epub 2013 Dec 11. Proc Natl Acad Sci U S A. 2014. PMID: 24335589 Free PMC article.
44 results