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A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade.
Geuijen C, Tacken P, Wang LC, Klooster R, van Loo PF, Zhou J, Mondal A, Liu YB, Kramer A, Condamine T, Volgina A, Hendriks LJA, van der Maaden H, Rovers E, Engels S, Fransen F, den Blanken-Smit R, Zondag-van der Zande V, Basmeleh A, Bartelink W, Kulkarni A, Marissen W, Huang CY, Hall L, Harvey S, Kim S, Martinez M, O'Brien S, Moon E, Albelda S, Kanellopoulou C, Stewart S, Nastri H, Bakker ABH, Scherle P, Logtenberg T, Hollis G, de Kruif J, Huber R, Mayes PA, Throsby M. Geuijen C, et al. Among authors: bakker abh. Nat Commun. 2021 Jul 21;12(1):4445. doi: 10.1038/s41467-021-24767-5. Nat Commun. 2021. PMID: 34290245 Free PMC article.
MCLA-117, a CLEC12AxCD3 bispecific antibody targeting a leukaemic stem cell antigen, induces T cell-mediated AML blast lysis.
van Loo PF, Hangalapura BN, Thordardottir S, Gibbins JD, Veninga H, Hendriks LJA, Kramer A, Roovers RC, Leenders M, de Kruif J, Doornbos RP, Sirulnik A, Throsby M, Logtenberg T, Dolstra H, Bakker ABH. van Loo PF, et al. Among authors: bakker abh. Expert Opin Biol Ther. 2019 Jul;19(7):721-733. doi: 10.1080/14712598.2019.1623200. Expert Opin Biol Ther. 2019. PMID: 31286786
Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose.
de Vries Schultink AHM, Doornbos RP, Bakker ABH, Bol K, Throsby M, Geuijen C, Maussang D, Schellens JHM, Beijnen JH, Huitema ADR. de Vries Schultink AHM, et al. Among authors: bakker abh. Invest New Drugs. 2018 Dec;36(6):1006-1015. doi: 10.1007/s10637-018-0593-x. Epub 2018 May 5. Invest New Drugs. 2018. PMID: 29728897 Free PMC article.
C-type lectin-like molecule-1: a novel myeloid cell surface marker associated with acute myeloid leukemia.
Bakker AB, van den Oudenrijn S, Bakker AQ, Feller N, van Meijer M, Bia JA, Jongeneelen MA, Visser TJ, Bijl N, Geuijen CA, Marissen WE, Radosevic K, Throsby M, Schuurhuis GJ, Ossenkoppele GJ, de Kruif J, Goudsmit J, Kruisbeek AM. Bakker AB, et al. Cancer Res. 2004 Nov 15;64(22):8443-50. doi: 10.1158/0008-5472.CAN-04-1659. Cancer Res. 2004. PMID: 15548716
Novel rabies virus-neutralizing epitope recognized by human monoclonal antibody: fine mapping and escape mutant analysis.
Marissen WE, Kramer RA, Rice A, Weldon WC, Niezgoda M, Faber M, Slootstra JW, Meloen RH, Clijsters-van der Horst M, Visser TJ, Jongeneelen M, Thijsse S, Throsby M, de Kruif J, Rupprecht CE, Dietzschold B, Goudsmit J, Bakker AB. Marissen WE, et al. J Virol. 2005 Apr;79(8):4672-8. doi: 10.1128/JVI.79.8.4672-4678.2005. J Virol. 2005. PMID: 15795253 Free PMC article.
Molecular and biological characterization of human monoclonal antibodies binding to the spike and nucleocapsid proteins of severe acute respiratory syndrome coronavirus.
van den Brink EN, Ter Meulen J, Cox F, Jongeneelen MA, Thijsse A, Throsby M, Marissen WE, Rood PM, Bakker AB, Gelderblom HR, Martina BE, Osterhaus AD, Preiser W, Doerr HW, de Kruif J, Goudsmit J. van den Brink EN, et al. J Virol. 2005 Feb;79(3):1635-44. doi: 10.1128/JVI.79.3.1635-1644.2005. J Virol. 2005. PMID: 15650189 Free PMC article.
16 results