Baker TS - Search Results

1

Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling.

Adams R, Burnley RJ, Valenzano CR, Qureshi O, Doyle C, Lumb S, Del Carmen Lopez M, Griffin R, McMillan D, Taylor RD, Meier C, Mori P, Griffin LM, Wernery U, Kinne J, Rapecki S, Baker TS, Lawson AD, Wright M, Ettorre A. Adams R, et al. Among authors: baker ts. Sci Rep. 2017 Jan 30;7:37716. doi: 10.1038/srep37716. Sci Rep. 2017. PMID: 28134246 Free PMC article.

2

Conservation of functional sites on interleukin-6 and implications for evolution of signaling complex assembly and therapeutic intervention.

Veverka V, Baker T, Redpath NT, Carrington B, Muskett FW, Taylor RJ, Lawson AD, Henry AJ, Carr MD. Veverka V, et al. J Biol Chem. 2012 Nov 16;287(47):40043-50. doi: 10.1074/jbc.M112.405597. Epub 2012 Oct 1. J Biol Chem. 2012. PMID: 23027872 Free PMC article.

3

¹⁵N, ¹³C and ¹H resonance assignments and secondary structure determination of a variable heavy domain of a heavy chain antibody.

Prosser CE, Waters LC, Muskett FW, Veverka V, Addis PW, Griffin LM, Baker TS, Lawson AD, Wernery U, Kinne J, Henry AJ, Taylor RJ, Carr MD. Prosser CE, et al. Among authors: baker ts. Biomol NMR Assign. 2014 Apr;8(1):113-6. doi: 10.1007/s12104-013-9464-8. Epub 2013 Jan 29. Biomol NMR Assign. 2014. PMID: 23359223

4

Analysis of heavy and light chain sequences of conventional camelid antibodies from Camelus dromedarius and Camelus bactrianus species.

Griffin LM, Snowden JR, Lawson AD, Wernery U, Kinne J, Baker TS. Griffin LM, et al. Among authors: baker ts. J Immunol Methods. 2014 Mar;405:35-46. doi: 10.1016/j.jim.2014.01.003. Epub 2014 Jan 18. J Immunol Methods. 2014. PMID: 24444705 Free article.

5

Discovery and characterization of olokizumab: a humanized antibody targeting interleukin-6 and neutralizing gp130-signaling.

Shaw S, Bourne T, Meier C, Carrington B, Gelinas R, Henry A, Popplewell A, Adams R, Baker T, Rapecki S, Marshall D, Moore A, Neale H, Lawson A. Shaw S, et al. MAbs. 2014 May-Jun;6(3):774-82. doi: 10.4161/mabs.28612. Epub 2014 Apr 2. MAbs. 2014. PMID: 24670876 Free PMC article.

6

Creation of a gated antibody as a conditionally functional synthetic protein.

Gunnoo SB, Finney HM, Baker TS, Lawson AD, Anthony DC, Davis BG. Gunnoo SB, et al. Among authors: baker ts. Nat Commun. 2014 Jul 30;5:4388. doi: 10.1038/ncomms5388. Nat Commun. 2014. PMID: 25073737 Free PMC article.

7

Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life.

Adams R, Griffin L, Compson JE, Jairaj M, Baker T, Ceska T, West S, Zaccheo O, Davé E, Lawson AD, Humphreys DP, Heywood S. Adams R, et al. MAbs. 2016 Oct;8(7):1336-1346. doi: 10.1080/19420862.2016.1185581. Epub 2016 Jun 17. MAbs. 2016. PMID: 27315033 Free PMC article.

8

Computational design of an epitope-specific Keap1 binding antibody using hotspot residues grafting and CDR loop swapping.

Liu X, Taylor RD, Griffin L, Coker SF, Adams R, Ceska T, Shi J, Lawson AD, Baker T. Liu X, et al. Sci Rep. 2017 Jan 27;7:41306. doi: 10.1038/srep41306. Sci Rep. 2017. PMID: 28128368 Free PMC article.

9

Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation.

Glatt S, Baeten D, Baker T, Griffiths M, Ionescu L, Lawson ADG, Maroof A, Oliver R, Popa S, Strimenopoulou F, Vajjah P, Watling MIL, Yeremenko N, Miossec P, Shaw S. Glatt S, et al. Ann Rheum Dis. 2018 Apr;77(4):523-532. doi: 10.1136/annrheumdis-2017-212127. Epub 2017 Dec 23. Ann Rheum Dis. 2018. PMID: 29275332 Free PMC article. Clinical Trial.

10

Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau.

Courade JP, Angers R, Mairet-Coello G, Pacico N, Tyson K, Lightwood D, Munro R, McMillan D, Griffin R, Baker T, Starkie D, Nan R, Westwood M, Mushikiwabo ML, Jung S, Odede G, Sweeney B, Popplewell A, Burgess G, Downey P, Citron M. Courade JP, et al. Acta Neuropathol. 2018 Nov;136(5):729-745. doi: 10.1007/s00401-018-1911-2. Epub 2018 Sep 20. Acta Neuropathol. 2018. PMID: 30238240 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

232 results

Search Page