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Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity.
Snarr BD, Baker P, Bamford NC, Sato Y, Liu H, Lehoux M, Gravelat FN, Ostapska H, Baistrocchi SR, Cerone RP, Filler EE, Parsek MR, Filler SG, Howell PL, Sheppard DC. Snarr BD, et al. Among authors: baker p. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7124-7129. doi: 10.1073/pnas.1702798114. Epub 2017 Jun 20. Proc Natl Acad Sci U S A. 2017. PMID: 28634301 Free PMC article.
P. aeruginosa SGNH hydrolase-like proteins AlgJ and AlgX have similar topology but separate and distinct roles in alginate acetylation.
Baker P, Ricer T, Moynihan PJ, Kitova EN, Walvoort MT, Little DJ, Whitney JC, Dawson K, Weadge JT, Robinson H, Ohman DE, Codée JD, Klassen JS, Clarke AJ, Howell PL. Baker P, et al. PLoS Pathog. 2014 Aug 28;10(8):e1004334. doi: 10.1371/journal.ppat.1004334. eCollection 2014 Aug. PLoS Pathog. 2014. PMID: 25165982 Free PMC article.
PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β(1,6)-N-acetylglucosamine and can disrupt bacterial biofilms.
Little DJ, Pfoh R, Le Mauff F, Bamford NC, Notte C, Baker P, Guragain M, Robinson H, Pier GB, Nitz M, Deora R, Sheppard DC, Howell PL. Little DJ, et al. Among authors: baker p. PLoS Pathog. 2018 Apr 23;14(4):e1006998. doi: 10.1371/journal.ppat.1006998. eCollection 2018 Apr. PLoS Pathog. 2018. PMID: 29684093 Free PMC article.
Treatment with the Pseudomonas aeruginosa Glycoside Hydrolase PslG Combats Wound Infection by Improving Antibiotic Efficacy and Host Innate Immune Activity.
Pestrak MJ, Baker P, Dellos-Nolan S, Hill PJ, Passos da Silva D, Silver H, Lacdao I, Raju D, Parsek MR, Wozniak DJ, Howell PL. Pestrak MJ, et al. Among authors: baker p. Antimicrob Agents Chemother. 2019 May 24;63(6):e00234-19. doi: 10.1128/AAC.00234-19. Print 2019 Jun. Antimicrob Agents Chemother. 2019. PMID: 30988141 Free PMC article.
2,912 results