Baker BM - Search Results

1

HLA class-I-peptide stability mediates CD8⁺ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV.

Kaseke C, Park RJ, Singh NK, Koundakjian D, Bashirova A, Garcia Beltran WF, Takou Mbah OC, Ma J, Senjobe F, Urbach JM, Nathan A, Rossin EJ, Tano-Menka R, Khatri A, Piechocka-Trocha A, Waring MT, Birnbaum ME, Baker BM, Carrington M, Walker BD, Gaiha GD. Kaseke C, et al. Among authors: baker bm. Cell Rep. 2021 Jul 13;36(2):109378. doi: 10.1016/j.celrep.2021.109378. Cell Rep. 2021. PMID: 34260940 Free PMC article.

2

Computational design of the affinity and specificity of a therapeutic T cell receptor.

Pierce BG, Hellman LM, Hossain M, Singh NK, Vander Kooi CW, Weng Z, Baker BM. Pierce BG, et al. Among authors: baker bm. PLoS Comput Biol. 2014 Feb 13;10(2):e1003478. doi: 10.1371/journal.pcbi.1003478. eCollection 2014 Feb. PLoS Comput Biol. 2014. PMID: 24550723 Free PMC article.

3

Changing the peptide specificity of a human T-cell receptor by directed evolution.

Smith SN, Wang Y, Baylon JL, Singh NK, Baker BM, Tajkhorshid E, Kranz DM. Smith SN, et al. Among authors: baker bm. Nat Commun. 2014 Nov 7;5:5223. doi: 10.1038/ncomms6223. Nat Commun. 2014. PMID: 25376839 Free PMC article.

4

Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.

Adams JJ, Narayanan S, Birnbaum ME, Sidhu SS, Blevins SJ, Gee MH, Sibener LV, Baker BM, Kranz DM, Garcia KC. Adams JJ, et al. Among authors: baker bm. Nat Immunol. 2016 Jan;17(1):87-94. doi: 10.1038/ni.3310. Epub 2015 Nov 2. Nat Immunol. 2016. PMID: 26523866 Free PMC article.

5

How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire.

Blevins SJ, Pierce BG, Singh NK, Riley TP, Wang Y, Spear TT, Nishimura MI, Weng Z, Baker BM. Blevins SJ, et al. Among authors: baker bm. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1276-85. doi: 10.1073/pnas.1522069113. Epub 2016 Feb 16. Proc Natl Acad Sci U S A. 2016. PMID: 26884163 Free PMC article.

6

Computational Reprogramming of T Cell Antigen Receptor Binding Properties.

Riley TP, Singh NK, Pierce BG, Baker BM, Weng Z. Riley TP, et al. Among authors: baker bm. Methods Mol Biol. 2016;1414:305-18. doi: 10.1007/978-1-4939-3569-7_18. Methods Mol Biol. 2016. PMID: 27094299

7

Computational Modeling of T Cell Receptor Complexes.

Riley TP, Singh NK, Pierce BG, Weng Z, Baker BM. Riley TP, et al. Among authors: baker bm. Methods Mol Biol. 2016;1414:319-40. doi: 10.1007/978-1-4939-3569-7_19. Methods Mol Biol. 2016. PMID: 27094300

8

An Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry.

Harris DT, Singh NK, Cai Q, Smith SN, Vander Kooi C, Procko E, Kranz DM, Baker BM. Harris DT, et al. Among authors: baker bm. Structure. 2016 Jul 6;24(7):1142-1154. doi: 10.1016/j.str.2016.04.011. Epub 2016 May 26. Structure. 2016. PMID: 27238970 Free PMC article.

9

A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces.

Riley TP, Ayres CM, Hellman LM, Singh NK, Cosiano M, Cimons JM, Anderson MJ, Piepenbrink KH, Pierce BG, Weng Z, Baker BM. Riley TP, et al. Among authors: baker bm. Protein Eng Des Sel. 2016 Dec;29(12):595-606. doi: 10.1093/protein/gzw050. Epub 2016 Sep 13. Protein Eng Des Sel. 2016. PMID: 27624308 Free PMC article.

10

Deep Mutational Scans as a Guide to Engineering High Affinity T Cell Receptor Interactions with Peptide-bound Major Histocompatibility Complex.

Harris DT, Wang N, Riley TP, Anderson SD, Singh NK, Procko E, Baker BM, Kranz DM. Harris DT, et al. Among authors: baker bm. J Biol Chem. 2016 Nov 18;291(47):24566-24578. doi: 10.1074/jbc.M116.748681. Epub 2016 Sep 28. J Biol Chem. 2016. PMID: 27681597 Free PMC article.

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