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Regulatory T-cell impairment in cystic fibrosis patients with chronic pseudomonas infection.
Hector A, Schäfer H, Pöschel S, Fischer A, Fritzsching B, Ralhan A, Carevic M, Öz H, Zundel S, Hogardt M, Bakele M, Rieber N, Riethmueller J, Graepler-Mainka U, Stahl M, Bender A, Frick JS, Mall M, Hartl D. Hector A, et al. Among authors: bakele m. Am J Respir Crit Care Med. 2015 Apr 15;191(8):914-23. doi: 10.1164/rccm.201407-1381OC. Am J Respir Crit Care Med. 2015. PMID: 25632992
Localization and functionality of the inflammasome in neutrophils.
Bakele M, Joos M, Burdi S, Allgaier N, Pöschel S, Fehrenbacher B, Schaller M, Marcos V, Kümmerle-Deschner J, Rieber N, Borregaard N, Yazdi A, Hector A, Hartl D. Bakele M, et al. J Biol Chem. 2014 Feb 21;289(8):5320-9. doi: 10.1074/jbc.M113.505636. Epub 2014 Jan 7. J Biol Chem. 2014. PMID: 24398679 Free PMC article.
Neutrophils express distinct RNA receptors in a non-canonical way.
Berger M, Hsieh CY, Bakele M, Marcos V, Rieber N, Kormann M, Mays L, Hofer L, Neth O, Vitkov L, Krautgartner WD, von Schweinitz D, Kappler R, Hector A, Weber A, Hartl D. Berger M, et al. Among authors: bakele m. J Biol Chem. 2012 Jun 1;287(23):19409-17. doi: 10.1074/jbc.M112.353557. Epub 2012 Apr 24. J Biol Chem. 2012. PMID: 22532562 Free PMC article. Clinical Trial.
In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency.
Mahiny AJ, Dewerth A, Mays LE, Alkhaled M, Mothes B, Malaeksefat E, Loretz B, Rottenberger J, Brosch DM, Reautschnig P, Surapolchai P, Zeyer F, Schams A, Carevic M, Bakele M, Griese M, Schwab M, Nürnberg B, Beer-Hammer S, Handgretinger R, Hartl D, Lehr CM, Kormann MS. Mahiny AJ, et al. Among authors: bakele m. Nat Biotechnol. 2015 Jun;33(6):584-6. doi: 10.1038/nbt.3241. Epub 2015 May 18. Nat Biotechnol. 2015. PMID: 25985262 No abstract available.