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Does Δ133p53 isoform trigger inflammation and autoimmunity?
Campbell HG, Slatter TL, Jeffs A, Mehta R, Rubio C, Baird M, Braithwaite AW. Campbell HG, et al. Cell Cycle. 2012 Feb 1;11(3):446-50. doi: 10.4161/cc.11.3.19054. Epub 2012 Feb 1. Cell Cycle. 2012. PMID: 22262184
∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling.
Campbell H, Fleming N, Roth I, Mehta S, Wiles A, Williams G, Vennin C, Arsic N, Parkin A, Pajic M, Munro F, McNoe L, Black M, McCall J, Slatter TL, Timpson P, Reddel R, Roux P, Print C, Baird MA, Braithwaite AW. Campbell H, et al. Among authors: baird ma. Nat Commun. 2018 Jan 17;9(1):254. doi: 10.1038/s41467-017-02408-0. Nat Commun. 2018. PMID: 29343721 Free PMC article.
The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer.
Kazantseva M, Mehta S, Eiholzer RA, Gimenez G, Bowie S, Campbell H, Reily-Bell AL, Roth I, Ray S, Drummond CJ, Reid G, Joruiz SM, Wiles A, Morrin HR, Reader KL, Hung NA, Baird MA, Slatter TL, Braithwaite AW. Kazantseva M, et al. Among authors: baird ma. Cell Death Dis. 2019 Aug 20;10(9):631. doi: 10.1038/s41419-019-1861-1. Cell Death Dis. 2019. PMID: 31431617 Free PMC article.
Antitumor cytotoxicity induced by bone-marrow-derived antigen-presenting cells is facilitated by the tumor suppressor protein p53 via regulation of IL-12.
Slatter TL, Wilson M, Tang C, Campbell HG, Ward VK, Young VL, Van Ly D, Fleming NI, Braithwaite AW, Baird MA. Slatter TL, et al. Among authors: baird ma. Oncoimmunology. 2015 Dec 17;5(3):e1112941. doi: 10.1080/2162402X.2015.1112941. eCollection 2016 Mar. Oncoimmunology. 2015. PMID: 27141366 Free PMC article.
189 results