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Forward genetics identifies a novel sleep mutant with sleep state inertia and REM sleep deficits.
Banks GT, Guillaumin MCC, Heise I, Lau P, Yin M, Bourbia N, Aguilar C, Bowl MR, Esapa C, Brown LA, Hasan S, Tagliatti E, Nicholson E, Bains RS, Wells S, Vyazovskiy VV, Volynski K, Peirson SN, Nolan PM. Banks GT, et al. Among authors: bains rs. Sci Adv. 2020 Aug 12;6(33):eabb3567. doi: 10.1126/sciadv.abb3567. eCollection 2020 Aug. Sci Adv. 2020. PMID: 32851175 Free PMC article.
Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety.
Moir L, Bochukova EG, Dumbell R, Banks G, Bains RS, Nolan PM, Scudamore C, Simon M, Watson KA, Keogh J, Henning E, Hendricks A, O'Rahilly S, Barroso I; UK10K consortium; Sullivan AE, Bersten DC, Whitelaw ML, Kirsch S, Bentley E, Farooqi IS, Cox RD. Moir L, et al. Among authors: bains rs. Mol Metab. 2017 Nov;6(11):1419-1428. doi: 10.1016/j.molmet.2017.08.006. Epub 2017 Aug 24. Mol Metab. 2017. PMID: 29107289 Free PMC article.
Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities.
Stewart M, Lau P, Banks G, Bains RS, Castroflorio E, Oliver PL, Dixon CL, Kruer MC, Kullmann DM, Acevedo-Arozena A, Wells SE, Corrochano S, Nolan PM. Stewart M, et al. Among authors: bains rs. Dis Model Mech. 2019 Feb 22;12(2):dmm036806. doi: 10.1242/dmm.036806. Dis Model Mech. 2019. PMID: 30692144 Free PMC article.
Longitudinal home-cage automated assessment of climbing behavior shows sexual dimorphism and aging-related decrease in C57BL/6J healthy mice and allows early detection of motor impairment in the N171-82Q mouse model of Huntington's disease.
Bains RS, Forrest H, Sillito RR, Armstrong JD, Stewart M, Nolan PM, Wells SE. Bains RS, et al. Front Behav Neurosci. 2023 Mar 22;17:1148172. doi: 10.3389/fnbeh.2023.1148172. eCollection 2023. Front Behav Neurosci. 2023. PMID: 37035623 Free PMC article.
32 results