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Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore.
Lim YC, Ensbey KS, Offenhäuser C, D'souza RCJ, Cullen JK, Stringer BW, Quek H, Bruce ZC, Kijas A, Cianfanelli V, Mahboubi B, Smith F, Jeffree RL, Wiesmüeller L, Wiegmans AP, Bain A, Lombard FJ, Roberts TL, Khanna KK, Lavin MF, Kim B, Hamerlik P, Johns TG, Coster MJ, Boyd AW, Day BW. Lim YC, et al. Among authors: bain a. Neuro Oncol. 2020 Feb 20;22(2):216-228. doi: 10.1093/neuonc/noz159. Neuro Oncol. 2020. PMID: 31504812 Free PMC article.
Mouse models uncap novel roles of SSBs.
Bain AL, Shi W, Khanna KK. Bain AL, et al. Cell Res. 2013 Jun;23(6):744-5. doi: 10.1038/cr.2013.63. Epub 2013 May 7. Cell Res. 2013. PMID: 23649314 Free PMC article.
Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae.
Kalimutho M, Bain AL, Mukherjee B, Nag P, Nanayakkara DM, Harten SK, Harris JL, Subramanian GN, Sinha D, Shirasawa S, Srihari S, Burma S, Khanna KK. Kalimutho M, et al. Mol Oncol. 2017 May;11(5):470-490. doi: 10.1002/1878-0261.12040. Epub 2017 Mar 27. Mol Oncol. 2017. PMID: 28173629 Free PMC article.
Long Noncoding RNAs CUPID1 and CUPID2 Mediate Breast Cancer Risk at 11q13 by Modulating the Response to DNA Damage.
Betts JA, Moradi Marjaneh M, Al-Ejeh F, Lim YC, Shi W, Sivakumaran H, Tropée R, Patch AM, Clark MB, Bartonicek N, Wiegmans AP, Hillman KM, Kaufmann S, Bain AL, Gloss BS, Crawford J, Kazakoff S, Wani S, Wen SW, Day B, Möller A, Cloonan N, Pearson J, Brown MA, Mercer TR, Waddell N, Khanna KK, Dray E, Dinger ME, Edwards SL, French JD. Betts JA, et al. Among authors: bain al. Am J Hum Genet. 2017 Aug 3;101(2):255-266. doi: 10.1016/j.ajhg.2017.07.007. Am J Hum Genet. 2017. PMID: 28777932 Free PMC article.
Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling.
Sinha D, Kalimutho M, Bowles J, Chan AL, Merriner DJ, Bain AL, Simmons JL, Freire R, Lopez JA, Hobbs RM, O'Bryan MK, Khanna KK. Sinha D, et al. FASEB J. 2018 Sep;32(9):4984-4999. doi: 10.1096/fj.201701096RR. Epub 2018 Apr 17. FASEB J. 2018. PMID: 29683733
Spermatogenesis is a dynamic process involving self-renewal and differentiation of spermatogonial stem cells, meiosis, and ultimately, the differentiation of haploid spermatids into sperm. ...-Sinha, D., Kalimutho, M., Bowles, J., Chan, A.-L., Merriner, D. J., Ba …
Spermatogenesis is a dynamic process involving self-renewal and differentiation of spermatogonial stem cells, meiosis, and ultimately …
363 results