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Synthesis and Structure-Activity Relationships of N-(4-Benzamidino)-Oxazolidinones: Potent and Selective Inhibitors of Kallikrein-Related Peptidase 6.
De Vita E, Smits N, van den Hurk H, Beck EM, Hewitt J, Baillie G, Russell E, Pannifer A, Hamon V, Morrison A, McElroy SP, Jones P, Ignatenko NA, Gunkel N, Miller AK. De Vita E, et al. Among authors: baillie g. ChemMedChem. 2020 Jan 7;15(1):79-95. doi: 10.1002/cmdc.201900536. Epub 2019 Nov 18. ChemMedChem. 2020. PMID: 31675166 Free PMC article.
A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives.
Lazzari P, Distinto R, Manca I, Baillie G, Murineddu G, Pira M, Falzoi M, Sani M, Morales P, Ross R, Zanda M, Jagerovic N, Pinna GA. Lazzari P, et al. Among authors: baillie g. Eur J Med Chem. 2016 Oct 4;121:194-208. doi: 10.1016/j.ejmech.2016.05.011. Epub 2016 May 6. Eur J Med Chem. 2016. PMID: 27240274
The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators.
Tseng CC, Baillie G, Donvito G, Mustafa MA, Juola SE, Zanato C, Massarenti C, Dall'Angelo S, Harrison WTA, Lichtman AH, Ross RA, Zanda M, Greig IR. Tseng CC, et al. Among authors: baillie g. J Med Chem. 2019 May 23;62(10):5049-5062. doi: 10.1021/acs.jmedchem.9b00252. Epub 2019 May 14. J Med Chem. 2019. PMID: 31050898 Free PMC article.
314 results