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Empagliflozin Inhibits Cardiac Late Sodium Current by Ca/Calmodulin-Dependent Kinase II.
Mustroph J, Baier MJ, Pabel S, Stehle T, Trum M, Provaznik Z, Mohler PJ, Musa H, Hund TJ, Sossalla S, Maier LS, Wagner S. Mustroph J, et al. Among authors: baier mj. Circulation. 2022 Oct 18;146(16):1259-1261. doi: 10.1161/CIRCULATIONAHA.122.057364. Epub 2022 Oct 17. Circulation. 2022. PMID: 36251785 Free PMC article. No abstract available.
The novel CaMKII inhibitor GS-680 reduces diastolic SR Ca leak and prevents CaMKII-dependent pro-arrhythmic activity.
Lebek S, Plößl A, Baier M, Mustroph J, Tarnowski D, Lücht CM, Schopka S, Flörchinger B, Schmid C, Zausig Y, Pagratis N, Marchand B, Koltun DO, Hung WK, Ahmadyar S, Belardinelli L, Maier LS, Wagner S. Lebek S, et al. J Mol Cell Cardiol. 2018 May;118:159-168. doi: 10.1016/j.yjmcc.2018.03.020. Epub 2018 Mar 31. J Mol Cell Cardiol. 2018. PMID: 29614261
The oral Ca/calmodulin-dependent kinase II inhibitor RA608 improves contractile function and prevents arrhythmias in heart failure.
Mustroph J, Drzymalski M, Baier M, Pabel S, Biedermann A, Memmel B, Durczok M, Neef S, Sag CM, Floerchinger B, Rupprecht L, Schmid C, Zausig Y, Bégis G, Briand V, Ozoux ML, Tamarelle D, Ballet V, Janiak P, Beauverger P, Maier LS, Wagner S. Mustroph J, et al. ESC Heart Fail. 2020 Oct;7(5):2871-2883. doi: 10.1002/ehf2.12895. Epub 2020 Jul 20. ESC Heart Fail. 2020. PMID: 32691522 Free PMC article.
Decreased GLUT1/NHE1 RNA expression in whole blood predicts disease severity in patients with COVID-19.
Mustroph J, Hupf J, Hanses F, Evert K, Baier MJ, Evert M, Meindl C, Wagner S, Hubauer U, Pietrzyk G, Leininger S, Staudner S, Vogel M, Wallner S, Zimmermann M, Sossalla S, Maier LS, Jungbauer C. Mustroph J, et al. Among authors: baier mj. ESC Heart Fail. 2021 Feb;8(1):309-316. doi: 10.1002/ehf2.13063. Epub 2020 Nov 20. ESC Heart Fail. 2021. PMID: 33215884 Free PMC article.
Loss of CASK Accelerates Heart Failure Development.
Mustroph J, Sag CM, Bähr F, Schmidtmann AL, Gupta SN, Dietz A, Islam MMT, Lücht C, Beuthner BE, Pabel S, Baier MJ, El-Armouche A, Sossalla S, Anderson ME, Möllmann J, Lehrke M, Marx N, Mohler PJ, Bers DM, Unsöld B, He T, Dewenter M, Backs J, Maier LS, Wagner S. Mustroph J, et al. Among authors: baier mj. Circ Res. 2021 Apr 16;128(8):1139-1155. doi: 10.1161/CIRCRESAHA.120.318170. Epub 2021 Feb 17. Circ Res. 2021. PMID: 33593074 Free PMC article.
18 results