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Peptidomimetic nitrile warheads as SARS-CoV-2 3CL protease inhibitors.
Bai B, Arutyunova E, Khan MB, Lu J, Joyce MA, Saffran HA, Shields JA, Kandadai AS, Belovodskiy A, Hena M, Vuong W, Lamer T, Young HS, Vederas JC, Tyrrell DL, Lemieux MJ, Nieman JA. Bai B, et al. RSC Med Chem. 2021 Aug 20;12(10):1722-1730. doi: 10.1039/d1md00247c. eCollection 2021 Oct 20. RSC Med Chem. 2021. PMID: 34778773 Free PMC article.
SARS-CoV-2 Mpro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals.
Chen SA, Arutyunova E, Lu J, Khan MB, Rut W, Zmudzinski M, Shahbaz S, Iyyathurai J, Moussa EW, Turner Z, Bai B, Lamer T, Nieman JA, Vederas JC, Julien O, Drag M, Elahi S, Young HS, Lemieux MJ. Chen SA, et al. Among authors: bai b. ACS Cent Sci. 2023 Mar 21;9(4):696-708. doi: 10.1021/acscentsci.3c00054. eCollection 2023 Apr 26. ACS Cent Sci. 2023. PMID: 37122453 Free PMC article.
Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and in Vitro Biological Stability.
Bai B, Belovodskiy A, Hena M, Kandadai AS, Joyce MA, Saffran HA, Shields JA, Khan MB, Arutyunova E, Lu J, Bajwa SK, Hockman D, Fischer C, Lamer T, Vuong W, van Belkum MJ, Gu Z, Lin F, Du Y, Xu J, Rahim M, Young HS, Vederas JC, Tyrrell DL, Lemieux MJ, Nieman JA. Bai B, et al. J Med Chem. 2022 Feb 24;65(4):2905-2925. doi: 10.1021/acs.jmedchem.1c00616. Epub 2021 Jul 9. J Med Chem. 2022. PMID: 34242027
Mental stress-induced myocardial ischemia detected by global longitudinal strain and quantitative myocardial contrast echocardiography in women with nonobstructive coronary artery disease.
Kong B, Fei H, Cheng S, Ma H, Yin H, Li M, Liu Q, Liu Y, Bai B, Liu F, Guo L, Geng Q. Kong B, et al. Among authors: bai b. J Am Soc Echocardiogr. 2024 May 16:S0894-7317(24)00231-1. doi: 10.1016/j.echo.2024.05.008. Online ahead of print. J Am Soc Echocardiogr. 2024. PMID: 38761987
Sintilimab (anti-PD-1 antibody) plus chidamide (histone deacetylase inhibitor) in relapsed or refractory extranodal natural killer T-cell lymphoma (SCENT): a phase Ib/II study.
Gao Y, He H, Li X, Zhang L, Xu W, Feng R, Li W, Xiao Y, Liu X, Chen Y, Wang X, Bai B, Wu H, Cai Q, Li Z, Li J, Lin S, He Y, Ping L, Huang C, Mao J, Chen X, Zhao B, Huang H. Gao Y, et al. Among authors: bai b. Signal Transduct Target Ther. 2024 May 17;9(1):121. doi: 10.1038/s41392-024-01825-0. Signal Transduct Target Ther. 2024. PMID: 38755119 Free PMC article. Clinical Trial.
1,512 results