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Cortical Organoids to Model Microcephaly.
Farcy S, Albert A, Gressens P, Baffet AD, El Ghouzzi V. Farcy S, et al. Among authors: baffet ad. Cells. 2022 Jul 7;11(14):2135. doi: 10.3390/cells11142135. Cells. 2022. PMID: 35883578 Free PMC article. Review.
A cell fate decision map reveals abundant direct neurogenesis bypassing intermediate progenitors in the human developing neocortex.
Coquand L, Brunet Avalos C, Macé AS, Farcy S, Di Cicco A, Lampic M, Wimmer R, Bessières B, Attie-Bitach T, Fraisier V, Sens P, Guimiot F, Brault JB, Baffet AD. Coquand L, et al. Among authors: baffet ad. Nat Cell Biol. 2024 May;26(5):698-709. doi: 10.1038/s41556-024-01393-z. Epub 2024 Mar 28. Nat Cell Biol. 2024. PMID: 38548890 Free PMC article.
WDR81 mutations cause extreme microcephaly and impair mitotic progression in human fibroblasts and Drosophila neural stem cells.
Cavallin M, Rujano MA, Bednarek N, Medina-Cano D, Bernabe Gelot A, Drunat S, Maillard C, Garfa-Traore M, Bole C, Nitschké P, Beneteau C, Besnard T, Cogné B, Eveillard M, Kuster A, Poirier K, Verloes A, Martinovic J, Bidat L, Rio M, Lyonnet S, Reilly ML, Boddaert N, Jenneson-Liver M, Motte J, Doco-Fenzy M, Chelly J, Attie-Bitach T, Simons M, Cantagrel V, Passemard S, Baffet A, Thomas S, Bahi-Buisson N. Cavallin M, et al. Brain. 2017 Oct 1;140(10):2597-2609. doi: 10.1093/brain/awx218. Brain. 2017. PMID: 28969387
Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity.
Kyrousi C, O'Neill AC, Brazovskaja A, He Z, Kielkowski P, Coquand L, Di Giaimo R, D' Andrea P, Belka A, Forero Echeverry A, Mei D, Lenge M, Cruceanu C, Buchsbaum IY, Khattak S, Fabien G, Binder E, Elmslie F, Guerrini R, Baffet AD, Sieber SA, Treutlein B, Robertson SP, Cappello S. Kyrousi C, et al. Among authors: baffet ad. Nat Commun. 2021 Nov 2;12(1):6298. doi: 10.1038/s41467-021-26447-w. Nat Commun. 2021. PMID: 34728600 Free PMC article.
Cerebral organoids display dynamic clonal growth and tunable tissue replenishment.
Lindenhofer D, Haendeler S, Esk C, Littleboy JB, Brunet Avalos C, Naas J, Pflug FG, van de Ven EGP, Reumann D, Baffet AD, von Haeseler A, Knoblich JA. Lindenhofer D, et al. Among authors: baffet ad. Nat Cell Biol. 2024 May;26(5):710-718. doi: 10.1038/s41556-024-01412-z. Epub 2024 May 7. Nat Cell Biol. 2024. PMID: 38714853 Free PMC article.
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