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The marine sponge-derived polyketide endoperoxide plakortide F acid mediates its antifungal activity by interfering with calcium homeostasis.
Xu T, Feng Q, Jacob MR, Avula B, Mask MM, Baerson SR, Tripathi SK, Mohammed R, Hamann MT, Khan IA, Walker LA, Clark AM, Agarwal AK. Xu T, et al. Among authors: baerson sr. Antimicrob Agents Chemother. 2011 Apr;55(4):1611-21. doi: 10.1128/AAC.01022-10. Epub 2011 Feb 7. Antimicrob Agents Chemother. 2011. PMID: 21300833 Free PMC article.
Two plant-derived aporphinoid alkaloids exert their antifungal activity by disrupting mitochondrial iron-sulfur cluster biosynthesis.
Tripathi SK, Xu T, Feng Q, Avula B, Shi X, Pan X, Mask MM, Baerson SR, Jacob MR, Ravu RR, Khan SI, Li XC, Khan IA, Clark AM, Agarwal AK. Tripathi SK, et al. Among authors: baerson sr. J Biol Chem. 2017 Oct 6;292(40):16578-16593. doi: 10.1074/jbc.M117.781773. Epub 2017 Aug 18. J Biol Chem. 2017. PMID: 28821607 Free PMC article.
38 results