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Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence.
Richardson JP, Mogavero S, Moyes DL, Blagojevic M, Krüger T, Verma AH, Coleman BM, De La Cruz Diaz J, Schulz D, Ponde NO, Carrano G, Kniemeyer O, Wilson D, Bader O, Enoiu SI, Ho J, Kichik N, Gaffen SL, Hube B, Naglik JR. Richardson JP, et al. Among authors: bader o. mBio. 2018 Jan 23;9(1):e02178-17. doi: 10.1128/mBio.02178-17. mBio. 2018. PMID: 29362237 Free PMC article.
Candidalysin is a fungal peptide toxin critical for mucosal infection.
Moyes DL, Wilson D, Richardson JP, Mogavero S, Tang SX, Wernecke J, Höfs S, Gratacap RL, Robbins J, Runglall M, Murciano C, Blagojevic M, Thavaraj S, Förster TM, Hebecker B, Kasper L, Vizcay G, Iancu SI, Kichik N, Häder A, Kurzai O, Luo T, Krüger T, Kniemeyer O, Cota E, Bader O, Wheeler RT, Gutsmann T, Hube B, Naglik JR. Moyes DL, et al. Among authors: bader o. Nature. 2016 Apr 7;532(7597):64-8. doi: 10.1038/nature17625. Epub 2016 Mar 30. Nature. 2016. PMID: 27027296 Free PMC article.
One small step for a yeast--microevolution within macrophages renders Candida glabrata hypervirulent due to a single point mutation.
Brunke S, Seider K, Fischer D, Jacobsen ID, Kasper L, Jablonowski N, Wartenberg A, Bader O, Enache-Angoulvant A, Schaller M, d'Enfert C, Hube B. Brunke S, et al. Among authors: bader o. PLoS Pathog. 2014 Oct 30;10(10):e1004478. doi: 10.1371/journal.ppat.1004478. eCollection 2014 Oct. PLoS Pathog. 2014. PMID: 25356907 Free PMC article.
Glycosylation of Candida albicans cell wall proteins is critical for induction of innate immune responses and apoptosis of epithelial cells.
Wagener J, Weindl G, de Groot PW, de Boer AD, Kaesler S, Thavaraj S, Bader O, Mailänder-Sanchez D, Borelli C, Weig M, Biedermann T, Naglik JR, Korting HC, Schaller M. Wagener J, et al. Among authors: bader o. PLoS One. 2012;7(11):e50518. doi: 10.1371/journal.pone.0050518. Epub 2012 Nov 30. PLoS One. 2012. PMID: 23226301 Free PMC article.
164 results