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The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice.
Cox AR, Masschelin PM, Saha PK, Felix JB, Sharp R, Lian Z, Xia Y, Chernis N, Bader DA, Kim KH, Li X, Yoshino J, Li X, Li G, Sun Z, Wu H, Coarfa C, Moore DD, Klein S, Sun K, Hartig SM. Cox AR, et al. Among authors: bader da. Cell Metab. 2022 Dec 6;34(12):1932-1946.e7. doi: 10.1016/j.cmet.2022.09.019. Epub 2022 Oct 14. Cell Metab. 2022. PMID: 36243005 Free PMC article.
STAT1 Dissociates Adipose Tissue Inflammation From Insulin Sensitivity in Obesity.
Cox AR, Chernis N, Bader DA, Saha PK, Masschelin PM, Felix JB, Sharp R, Lian Z, Putluri V, Rajapakshe K, Kim KH, Villareal DT, Armamento-Villareal R, Wu H, Coarfa C, Putluri N, Hartig SM. Cox AR, et al. Among authors: bader da. Diabetes. 2020 Dec;69(12):2630-2641. doi: 10.2337/db20-0384. Epub 2020 Sep 29. Diabetes. 2020. PMID: 32994273 Free PMC article.
The miRNA Interactome in Metabolic Homeostasis.
Hartig SM, Hamilton MP, Bader DA, McGuire SE. Hartig SM, et al. Among authors: bader da. Trends Endocrinol Metab. 2015 Dec;26(12):733-745. doi: 10.1016/j.tem.2015.09.006. Epub 2015 Oct 20. Trends Endocrinol Metab. 2015. PMID: 26492831 Free PMC article. Review.
Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer.
Bader DA, Hartig SM, Putluri V, Foley C, Hamilton MP, Smith EA, Saha PK, Panigrahi A, Walker C, Zong L, Martini-Stoica H, Chen R, Rajapakshe K, Coarfa C, Sreekumar A, Mitsiades N, Bankson JA, Ittmann MM, O'Malley BW, Putluri N, McGuire SE. Bader DA, et al. Nat Metab. 2019 Jan;1(1):70-85. doi: 10.1038/s42255-018-0002-y. Epub 2018 Nov 19. Nat Metab. 2019. PMID: 31198906 Free PMC article.
Ubc9 Impairs Activation of the Brown Fat Energy Metabolism Program in Human White Adipocytes.
Hartig SM, Bader DA, Abadie KV, Motamed M, Hamilton MP, Long W, York B, Mueller M, Wagner M, Trauner M, Chan L, Bajaj M, Moore DD, Mancini MA, McGuire SE. Hartig SM, et al. Among authors: bader da. Mol Endocrinol. 2015 Sep;29(9):1320-33. doi: 10.1210/me.2015-1084. Epub 2015 Jul 20. Mol Endocrinol. 2015. PMID: 26192107 Free PMC article.
Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice.
Ko MS, Yun JY, Baek IJ, Jang JE, Hwang JJ, Lee SE, Heo SH, Bader DA, Lee CH, Han J, Moon JS, Lee JM, Hong EG, Lee IK, Kim SW, Park JY, Hartig SM, Kang UJ, Moore DD, Koh EH, Lee KU. Ko MS, et al. Among authors: bader da. Autophagy. 2021 May;17(5):1205-1221. doi: 10.1080/15548627.2020.1753002. Epub 2020 May 13. Autophagy. 2021. PMID: 32400277 Free PMC article.
Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression.
Vantaku V, Putluri V, Bader DA, Maity S, Ma J, Arnold JM, Rajapakshe K, Donepudi SR, von Rundstedt FC, Devarakonda V, Dubrulle J, Karanam B, McGuire SE, Stossi F, Jain AK, Coarfa C, Cao Q, Sikora AG, Villanueva H, Kavuri SM, Lotan Y, Sreekumar A, Putluri N. Vantaku V, et al. Among authors: bader da. Oncogene. 2020 Oct;39(40):6265-6285. doi: 10.1038/s41388-019-0902-7. Epub 2019 Aug 5. Oncogene. 2020. PMID: 31383940 Free PMC article.
49 results