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Development of a Robust Manufacturing Route for Molnupiravir, an Antiviral for the Treatment of COVID-19.
Fier PS, Xu Y, Poirier M, Brito G, Zheng M, Bade R, Sirota E, Stone K, Tan L, Humphrey GR, Chang D, Bothe J, Zhang Y, Bernardoni F, Castro S, Zompa MA, Taylor J, Sirk KM, Diaz-Santana A, Diribe I, Emerson KM, Krishnamurthi B, Zhao R, Ward M, Xiao C, Ouyand H, Zhan J, Morris WJ. Fier PS, et al. Among authors: bade r. Org Process Res Dev. 2021 Dec 17;25(12):2806-2815. doi: 10.1021/acs.oprd.1c00400. Epub 2021 Dec 10. Org Process Res Dev. 2021. PMID: 35095257 Review.
Diverse Catalytic Reactions for the Stereoselective Synthesis of Cyclic Dinucleotide MK-1454.
Benkovics T, Peng F, Phillips EM, An C, Bade RS, Chung CK, Dance ZEX, Fier PS, Forstater JH, Liu Z, Liu Z, Maligres PE, Marshall NM, Salehi Marzijarani N, McIntosh JA, Miller SP, Moore JC, Neel AJ, Obligacion JV, Pan W, Pirnot MT, Poirier M, Reibarkh M, Sherry BD, Song ZJ, Tan L, Turnbull BWH, Verma D, Waldman JH, Wang L, Wang T, Winston MS, Xu F. Benkovics T, et al. J Am Chem Soc. 2022 Apr 6;144(13):5855-5863. doi: 10.1021/jacs.1c12106. Epub 2022 Mar 25. J Am Chem Soc. 2022. PMID: 35333525
A kinase-cGAS cascade to synthesize a therapeutic STING activator.
McIntosh JA, Liu Z, Andresen BM, Marzijarani NS, Moore JC, Marshall NM, Borra-Garske M, Obligacion JV, Fier PS, Peng F, Forstater JH, Winston MS, An C, Chang W, Lim J, Huffman MA, Miller SP, Tsay FR, Altman MD, Lesburg CA, Steinhuebel D, Trotter BW, Cumming JN, Northrup A, Bu X, Mann BF, Biba M, Hiraga K, Murphy GS, Kolev JN, Makarewicz A, Pan W, Farasat I, Bade RS, Stone K, Duan D, Alvizo O, Adpressa D, Guetschow E, Hoyt E, Regalado EL, Castro S, Rivera N, Smith JP, Wang F, Crespo A, Verma D, Axnanda S, Dance ZEX, Devine PN, Tschaen D, Canada KA, Bulger PG, Sherry BD, Truppo MD, Ruck RT, Campeau LC, Bennett DJ, Humphrey GR, Campos KR, Maddess ML. McIntosh JA, et al. Among authors: bade rs. Nature. 2022 Mar;603(7901):439-444. doi: 10.1038/s41586-022-04422-9. Epub 2022 Mar 16. Nature. 2022. PMID: 35296845
Seven-years of alcohol consumption in Australia by wastewater analysis: Exploring patterns by remoteness and socioeconomic factors.
Tscharke B, Livingston M, O'Brien JW, Bade R, Thomas KV, Mueller JF, Hall W, Simpson BS, Jaunay E, Gerber C, White JM, Thai PK. Tscharke B, et al. Among authors: bade r. Drug Alcohol Depend. 2024 Jun 1;259:111317. doi: 10.1016/j.drugalcdep.2024.111317. Epub 2024 Apr 26. Drug Alcohol Depend. 2024. PMID: 38692136 Free article.
Workflow to facilitate the detection of new psychoactive substances and drugs of abuse in influent urban wastewater.
Bade R, van Herwerden D, Rousis N, Adhikari S, Allen D, Baduel C, Bijlsma L, Boogaerts T, Burgard D, Chappell A, Driver EM, Sodre FF, Fatta-Kassinos D, Gracia-Lor E, Gracia-Marín E, Halden RU, Heath E, Jaunay E, Krotulski A, Lai FY, Löve ASC, O'Brien JW, Oh JE, Pasin D, Castro MP, Psichoudaki M, Salgueiro-Gonzalez N, Gomes CS, Subedi B, Thomas KV, Thomaidis N, Wang D, Yargeau V, Samanipour S, Mueller J. Bade R, et al. J Hazard Mater. 2024 May 5;469:133955. doi: 10.1016/j.jhazmat.2024.133955. Epub 2024 Mar 5. J Hazard Mater. 2024. PMID: 38457976 Free article.
Characterising differences between self-reported and wastewater-identified drug use at two consecutive years of an Australian music festival.
Puljević C, Tscharke B, Wessel EL, Francis C, Verhagen R, O'Brien JW, Bade R, Nadarajan D, Measham F, Stowe MJ, Piatkowski T, Ferris J, Page R, Hiley S, Eassey C, McKinnon G, Sinclair G, Blatchford E, Engel L, Norvill A, Barratt MJ. Puljević C, et al. Among authors: bade r. Sci Total Environ. 2024 Apr 15;921:170934. doi: 10.1016/j.scitotenv.2024.170934. Epub 2024 Feb 14. Sci Total Environ. 2024. PMID: 38360330 Free article.
103 results