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Phase 1 study of selinexor in combination with salvage chemotherapy in Adults with relapsed or refractory Acute myeloid leukemia.
Bhatnagar B, Zhao Q, Mims AS, Vasu S, Behbehani GK, Larkin K, Blachly JS, Badawi MA, Hill KL, Dzwigalski KR, Phelps MA, Blum W, Klisovic RB, Ruppert AS, Ranganathan P, Walker AR, Garzon R. Bhatnagar B, et al. Among authors: badawi ma. Leuk Lymphoma. 2023 Dec;64(13):2091-2100. doi: 10.1080/10428194.2023.2253480. Epub 2023 Sep 4. Leuk Lymphoma. 2023. PMID: 37665178 Clinical Trial.
Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells.
Zhu X, Badawi M, Pomeroy S, Sutaria DS, Xie Z, Baek A, Jiang J, Elgamal OA, Mo X, Perle K, Chalmers J, Schmittgen TD, Phelps MA. Zhu X, et al. Among authors: badawi m. J Extracell Vesicles. 2017 Jun 6;6(1):1324730. doi: 10.1080/20013078.2017.1324730. eCollection 2017. J Extracell Vesicles. 2017. PMID: 28717420 Free PMC article.
Pharmacokinetic-Pharmacodynamic Model of Neutropenia in Patients With Myeloma Receiving High-Dose Melphalan for Autologous Stem Cell Transplant.
Cho YK, Irby DJ, Li J, Sborov DW, Mould DR, Badawi M, Dauki A, Lamprecht M, Rosko AE, Fernandez S, Hade EM, Hofmeister CC, Poi M, Phelps MA. Cho YK, et al. Among authors: badawi m. CPT Pharmacometrics Syst Pharmacol. 2018 Nov;7(11):748-758. doi: 10.1002/psp4.12345. Epub 2018 Oct 20. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 30343510 Free PMC article.
A phase I study of an oral selective gamma secretase (GS) inhibitor RO4929097 in combination with neoadjuvant paclitaxel and carboplatin in triple negative breast cancer.
Sardesai S, Badawi M, Mrozek E, Morgan E, Phelps M, Stephens J, Wei L, Kassem M, Ling Y, Lustberg M, Stover D, Williams N, Layman R, Reinbolt R, VanDeusen J, Cherian M, Grever M, Carson W, Ramaswamy B, Wesolowski R. Sardesai S, et al. Invest New Drugs. 2020 Oct;38(5):1400-1410. doi: 10.1007/s10637-020-00895-5. Epub 2020 Jan 17. Invest New Drugs. 2020. PMID: 31953695 Free PMC article. Clinical Trial.
Early Intervention with Lenalidomide in Patients with High-risk Chronic Lymphocytic Leukemia.
Thangavadivel S, Zhao Q, Epperla N, Rike L, Mo X, Badawi M, Bystry DM, Phelps MA, Andritsos LA, Rogers KA, Jones J, Woyach JA, Byrd JC, Awan FT. Thangavadivel S, et al. Among authors: badawi m. Clin Cancer Res. 2020 Dec 1;26(23):6187-6195. doi: 10.1158/1078-0432.CCR-20-1280. Epub 2020 Sep 21. Clin Cancer Res. 2020. PMID: 32958702 Free PMC article. Clinical Trial.
Approaches to handling missing or "problematic" pharmacology data: Pharmacokinetics.
Irby DJ, Ibrahim ME, Dauki AM, Badawi MA, Illamola SM, Chen M, Wang Y, Liu X, Phelps MA, Mould DR. Irby DJ, et al. Among authors: badawi ma. CPT Pharmacometrics Syst Pharmacol. 2021 Apr;10(4):291-308. doi: 10.1002/psp4.12611. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 33715307 Free PMC article.
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