Investigating the role of zinc and copper binding motifs of trafficking sites in the cyanobacterium Synechocystis PCC 6803.
Badarau A, Baslé A, Firbank SJ, Dennison C.
Badarau A, et al.
Biochemistry. 2013 Oct 1;52(39):6816-23. doi: 10.1021/bi400492t. Epub 2013 Sep 19.
Biochemistry. 2013.
PMID: 24050657
Free PMC article.
However, the introduction of the ZiaAN motif (MDCTSC) dramatically increases the Zn(II) affinity of both Atx1 and PacSN by up to 2 orders of magnitude. The Atx1 mutant with the ZiaAN motif crystallizes as a side-to-side homodimer very similar to that found for [Cu(I)2-Atx1 …
However, the introduction of the ZiaAN motif (MDCTSC) dramatically increases the Zn(II) affinity of both Atx1 and PacSN by up to 2 orders of …