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An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers.
Mezheyeuski A, Backman M, Mattsson J, Martín-Bernabé A, Larsson C, Hrynchyk I, Hammarström K, Ström S, Ekström J, Mauchanski S, Khelashvili S, Lindberg A, Agnarsdóttir M, Edqvist PH, Huvila J, Segersten U, Malmström PU, Botling J, Nodin B, Hedner C, Borg D, Brändstedt J, Sartor H, Leandersson K, Glimelius B, Portyanko A, Ponten F, Jirström K, Micke P, Sjöblom T. Mezheyeuski A, et al. Among authors: backman m. EBioMedicine. 2023 Feb;88:104452. doi: 10.1016/j.ebiom.2023.104452. Epub 2023 Jan 30. EBioMedicine. 2023. PMID: 36724681 Free PMC article.
WITHDRAWN: Characterization of Patterns of Immune Cell Infiltration in NSCLC.
Backman M, La Fleur L, Kurppa P, Djureinovic D, Elfving H, Brunnström H, Mattsson JSM, Pontén V, Eltahir M, Mangsbo S, Isaksson J, Jirström K, Kärre K, Carbone E, Leandersson K, Mezheyeuski A, Pontén F, Lindskog C, Botling J, Micke P. Backman M, et al. J Thorac Oncol. 2020 Feb 4:S1556-0864(20)30015-0. doi: 10.1016/j.jtho.2019.12.127. Online ahead of print. J Thorac Oncol. 2020. PMID: 32028050
Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues.
Lindskog C, Backman M, Zieba A, Asplund A, Uhlén M, Landegren U, Pontén F. Lindskog C, et al. Among authors: backman m. J Histochem Cytochem. 2020 Jul;68(7):515-529. doi: 10.1369/0022155420936384. Epub 2020 Jun 30. J Histochem Cytochem. 2020. PMID: 32602410 Free PMC article.
Evaluation of NTRK immunohistochemistry as a screening method for NTRK gene fusion detection in non-small cell lung cancer.
Elfving H, Broström E, Moens LNJ, Almlöf J, Cerjan D, Lauter G, Nord H, Mattsson JSM, Ullenhag GJ, Strell C, Backman M, La Fleur L, Brunnström H, Botling J, Micke P. Elfving H, et al. Among authors: backman m. Lung Cancer. 2021 Jan;151:53-59. doi: 10.1016/j.lungcan.2020.11.023. Epub 2020 Nov 27. Lung Cancer. 2021. PMID: 33310622
PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung.
Goldmann T, Marwitz S, Nitschkowski D, Krupar R, Backman M, Elfving H, Thurfjell V, Lindberg A, Brunnström H, La Fleur L, Mezheyeuski A, Mattsson JSM, Botling J, Micke P, Strell C. Goldmann T, et al. Among authors: backman m. Cancer Immunol Immunother. 2021 Sep;70(9):2577-2587. doi: 10.1007/s00262-020-02825-z. Epub 2021 Feb 12. Cancer Immunol Immunother. 2021. PMID: 33576873 Free PMC article.
The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types.
Micke P, Strell C, Mattsson J, Martín-Bernabé A, Brunnström H, Huvila J, Sund M, Wärnberg F, Ponten F, Glimelius B, Hrynchyk I, Mauchanski S, Khelashvili S, Garcia-Vicién G, Molleví DG, Edqvist PH, O Reilly A, Corvigno S, Dahlstrand H, Botling J, Segersten U, Krzyzanowska A, Bjartell A, Elebro J, Heby M, Lundgren S, Hedner C, Borg D, Brändstedt J, Sartor H, Malmström PU, Johansson M, Nodin B, Backman M, Lindskog C, Jirström K, Mezheyeuski A. Micke P, et al. Among authors: backman m. EBioMedicine. 2021 Mar;65:103269. doi: 10.1016/j.ebiom.2021.103269. Epub 2021 Mar 9. EBioMedicine. 2021. PMID: 33706249 Free PMC article.
125 results