Backer JM - Search Results

1

Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ.

Erami Z, Khalil BD, Salloum G, Yao Y, LoPiccolo J, Shymanets A, Nürnberg B, Bresnick AR, Backer JM. Erami Z, et al. Among authors: backer jm. Biochem J. 2017 Nov 16;474(23):3903-3914. doi: 10.1042/BCJ20170279. Biochem J. 2017. PMID: 29046393 Free PMC article.

2

Fyn phosphorylates human MAP-2c on tyrosine 67.

Zamora-Leon SP, Bresnick A, Backer JM, Shafit-Zagardo B. Zamora-Leon SP, et al. Among authors: backer jm. J Biol Chem. 2005 Jan 21;280(3):1962-70. doi: 10.1074/jbc.M411380200. Epub 2004 Nov 9. J Biol Chem. 2005. PMID: 15536091 Free article.

3

Phospholipase C gamma negatively regulates Rac/Cdc42 activation in antigen-stimulated mast cells.

El-Sibai M, Backer JM. El-Sibai M, et al. Among authors: backer jm. Eur J Immunol. 2007 Jan;37(1):261-70. doi: 10.1002/eji.200635875. Eur J Immunol. 2007. PMID: 17163445 Free article.

4

The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration.

Yip SC, El-Sibai M, Coniglio SJ, Mouneimne G, Eddy RJ, Drees BE, Neilsen PO, Goswami S, Symons M, Condeelis JS, Backer JM. Yip SC, et al. Among authors: backer jm. J Cell Sci. 2007 Sep 1;120(Pt 17):3138-46. doi: 10.1242/jcs.005298. Epub 2007 Aug 14. J Cell Sci. 2007. PMID: 17698922 Free PMC article.

5

Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells.

El-Sibai M, Nalbant P, Pang H, Flinn RJ, Sarmiento C, Macaluso F, Cammer M, Condeelis JS, Hahn KM, Backer JM. El-Sibai M, et al. Among authors: backer jm. J Cell Sci. 2007 Oct 1;120(Pt 19):3465-74. doi: 10.1242/jcs.005942. Epub 2007 Sep 12. J Cell Sci. 2007. PMID: 17855387 Free PMC article.

6

Quantification of PtdIns(3,4,5)P(3) dynamics in EGF-stimulated carcinoma cells: a comparison of PH-domain-mediated methods with immunological methods.

Yip SC, Eddy RJ, Branch AM, Pang H, Wu H, Yan Y, Drees BE, Neilsen PO, Condeelis J, Backer JM. Yip SC, et al. Among authors: backer jm. Biochem J. 2008 Apr 15;411(2):441-8. doi: 10.1042/BJ20071179. Biochem J. 2008. PMID: 18215145 Free PMC article.

7

The regulation and function of Class III PI3Ks: novel roles for Vps34.

Backer JM. Backer JM. Biochem J. 2008 Feb 15;410(1):1-17. doi: 10.1042/BJ20071427. Biochem J. 2008. PMID: 18215151 Review.

8

In brain, Axl recruits Grb2 and the p85 regulatory subunit of PI3 kinase; in vitro mutagenesis defines the requisite binding sites for downstream Akt activation.

Weinger JG, Gohari P, Yan Y, Backer JM, Varnum B, Shafit-Zagardo B. Weinger JG, et al. Among authors: backer jm. J Neurochem. 2008 Jul;106(1):134-46. doi: 10.1111/j.1471-4159.2008.05343.x. Epub 2008 Jul 1. J Neurochem. 2008. PMID: 18346204 Free PMC article.

9

hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells.

Yan Y, Flinn RJ, Wu H, Schnur RS, Backer JM. Yan Y, et al. Among authors: backer jm. Biochem J. 2009 Feb 1;417(3):747-55. doi: 10.1042/BJ20081865. Biochem J. 2009. PMID: 18957027 Free PMC article.

10

Differential enhancement of breast cancer cell motility and metastasis by helical and kinase domain mutations of class IA phosphoinositide 3-kinase.

Pang H, Flinn R, Patsialou A, Wyckoff J, Roussos ET, Wu H, Pozzuto M, Goswami S, Condeelis JS, Bresnick AR, Segall JE, Backer JM. Pang H, et al. Among authors: backer jm. Cancer Res. 2009 Dec 1;69(23):8868-76. doi: 10.1158/0008-5472.CAN-09-1968. Epub 2009 Nov 10. Cancer Res. 2009. PMID: 19903845 Free PMC article.

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