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Novel potent bifunctional carboxylesterase inhibitors based on a polyfluoroalkyl-2-imino-1,3-dione scaffold.
Makhaeva GF, Lushchekina SV, Boltneva NP, Serebryakova OG, Kovaleva NV, Rudakova EV, Elkina NA, Shchegolkov EV, Burgart YV, Stupina TS, Terentiev AA, Radchenko EV, Palyulin VA, Saloutin VI, Bachurin SO, Richardson RJ. Makhaeva GF, et al. Among authors: bachurin so. Eur J Med Chem. 2021 Jun 5;218:113385. doi: 10.1016/j.ejmech.2021.113385. Epub 2021 Mar 15. Eur J Med Chem. 2021. PMID: 33831780
N,N-disubstituted 2-aminothiazolines as new inhibitors of serine esterases.
Boltneva NP, Serebryakova OG, Makhaeva GF, Serkov IV, Proshin AN, Bachurin SO. Boltneva NP, et al. Among authors: bachurin so. Dokl Biochem Biophys. 2013 Jul-Aug;451:209-11. doi: 10.1134/S160767291304011X. Epub 2013 Aug 23. Dokl Biochem Biophys. 2013. PMID: 23975403 No abstract available.
Novel bivalent positive allosteric modulators of AMPA receptor.
Lavrov MI, Grigor'ev VV, Bachurin SO, Palyulin VA, Zefirov NS. Lavrov MI, et al. Among authors: bachurin so. Dokl Biochem Biophys. 2015;464:322-4. doi: 10.1134/S1607672915050142. Epub 2015 Oct 31. Dokl Biochem Biophys. 2015. PMID: 26518559
Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors.
Makhaeva GF, Boltneva NP, Lushchekina SV, Serebryakova OG, Stupina TS, Terentiev AA, Serkov IV, Proshin AN, Bachurin SO, Richardson RJ. Makhaeva GF, et al. Among authors: bachurin so. Bioorg Med Chem. 2016 Mar 1;24(5):1050-62. doi: 10.1016/j.bmc.2016.01.031. Epub 2016 Jan 18. Bioorg Med Chem. 2016. PMID: 26827140
193 results