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Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis.
Torres S, Ortiz C, Bachtler N, Gu W, Grünewald LD, Kraus N, Schierwagen R, Hieber C, Meier C, Tyc O, Joseph Brol M, Uschner FE, Nijmeijer B, Welsch C, Berres ML, Garcia-Ruiz C, Fernandez-Checa JC, Trautwein C, Vogl TJ, Zeuzem S, Trebicka J, Klein S. Torres S, et al. Among authors: bachtler n. Hepatology. 2023 Apr 1;77(4):1228-1240. doi: 10.1002/hep.32746. Epub 2022 Oct 13. Hepatology. 2023. PMID: 35993369 Free PMC article.
The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis.
Torres S, Brol MJ, Magdaleno F, Schierwagen R, Uschner FE, Klein S, Ortiz C, Tyc O, Bachtler N, Stunden J, Bertheloot D, Kitanovic A, Sanchez B, Schrum J, Roush WR, Franchi L, Byth K, Latz E, Trebicka J. Torres S, et al. Among authors: bachtler n. Front Mol Biosci. 2021 Aug 13;8:715765. doi: 10.3389/fmolb.2021.715765. eCollection 2021. Front Mol Biosci. 2021. PMID: 34513923 Free PMC article.