Bachschmid MM - Search Results

1

Deficiency of endothelial sirtuin1 in mice stimulates skeletal muscle insulin sensitivity by modifying the secretome.

Li Q, Zhang Q, Kim YR, Gaddam RR, Jacobs JS, Bachschmid MM, Younis T, Zhu Z, Zingman L, London B, Rauckhorst AJ, Taylor EB, Norris AW, Vikram A, Irani K. Li Q, et al. Among authors: bachschmid mm. Nat Commun. 2023 Sep 11;14(1):5595. doi: 10.1038/s41467-023-41351-1. Nat Commun. 2023. PMID: 37696839 Free PMC article.

2

Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction.

Kumar S, Kim YR, Vikram A, Naqvi A, Li Q, Kassan M, Kumar V, Bachschmid MM, Jacobs JS, Kumar A, Irani K. Kumar S, et al. Among authors: bachschmid mm. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1714-1719. doi: 10.1073/pnas.1614112114. Epub 2017 Jan 30. Proc Natl Acad Sci U S A. 2017. PMID: 28137876 Free PMC article.

3

Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel.

Vikram A, Lewarchik CM, Yoon JY, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim YR, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung SB, Margulies KB, Kumar V, Bachschmid MM, London B, Irani K. Vikram A, et al. Among authors: bachschmid mm. Nat Med. 2017 Mar;23(3):361-367. doi: 10.1038/nm.4284. Epub 2017 Feb 13. Nat Med. 2017. PMID: 28191886 Free PMC article.

4

Aberrant Caspase Activation in Laminin-α2-Deficient Human Myogenic Cells is Mediated by p53 and Sirtuin Activity.

Yoon S, Beermann ML, Yu B, Shao D, Bachschmid M, Miller JB. Yoon S, et al. J Neuromuscul Dis. 2018;5(1):59-73. doi: 10.3233/JND-170262. J Neuromuscul Dis. 2018. PMID: 29278895 Free PMC article.

5

c-Jun N-terminal kinase 2 deficiency protects against hypercholesterolemia-induced endothelial dysfunction and oxidative stress.

Osto E, Matter CM, Kouroedov A, Malinski T, Bachschmid M, Camici GG, Kilic U, Stallmach T, Boren J, Iliceto S, Lüscher TF, Cosentino F. Osto E, et al. Circulation. 2008 Nov 11;118(20):2073-80. doi: 10.1161/CIRCULATIONAHA.108.765032. Epub 2008 Oct 27. Circulation. 2008. PMID: 18955669 Free article.

6

High-fat diet increases and the polyphenol, S17834, decreases acetylation of the sirtuin-1-dependent lysine-382 on p53 and apoptotic signaling in atherosclerotic lesion-prone aortic endothelium of normal mice.

Xu S, Jiang B, Hou X, Shi C, Bachschmid MM, Zang M, Verbeuren TJ, Cohen RA. Xu S, et al. Among authors: bachschmid mm. J Cardiovasc Pharmacol. 2011 Sep;58(3):263-71. doi: 10.1097/FJC.0b013e3182239eb7. J Cardiovasc Pharmacol. 2011. PMID: 21654327 Free PMC article.

7

Oxidized GAPDH transfers S-glutathionylation to a nuclear protein Sirtuin-1 leading to apoptosis.

Mustafa Rizvi SH, Shao D, Tsukahara Y, Pimentel DR, Weisbrod RM, Hamburg NM, McComb ME, Matsui R, Bachschmid MM. Mustafa Rizvi SH, et al. Among authors: bachschmid mm. Free Radic Biol Med. 2021 Oct;174:73-83. doi: 10.1016/j.freeradbiomed.2021.07.037. Epub 2021 Jul 28. Free Radic Biol Med. 2021. PMID: 34332079 Free PMC article.

8

Glutathione adducts induced by ischemia and deletion of glutaredoxin-1 stabilize HIF-1α and improve limb revascularization.

Watanabe Y, Murdoch CE, Sano S, Ido Y, Bachschmid MM, Cohen RA, Matsui R. Watanabe Y, et al. Among authors: bachschmid mm. Proc Natl Acad Sci U S A. 2016 May 24;113(21):6011-6. doi: 10.1073/pnas.1524198113. Epub 2016 May 9. Proc Natl Acad Sci U S A. 2016. PMID: 27162359 Free PMC article.

9

Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL.

Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT. Chitalia VC, et al. Among authors: bachschmid mm. Nat Cell Biol. 2008 Oct;10(10):1208-16. doi: 10.1038/ncb1781. Epub 2008 Sep 21. Nat Cell Biol. 2008. PMID: 18806787 Free PMC article.

10

S-glutathiolation of p21ras by peroxynitrite mediates endothelial insulin resistance caused by oxidized low-density lipoprotein.

Clavreul N, Bachschmid MM, Hou X, Shi C, Idrizovic A, Ido Y, Pimentel D, Cohen RA. Clavreul N, et al. Among authors: bachschmid mm. Arterioscler Thromb Vasc Biol. 2006 Nov;26(11):2454-61. doi: 10.1161/01.ATV.0000242791.28953.4c. Epub 2006 Aug 24. Arterioscler Thromb Vasc Biol. 2006. PMID: 16931794

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