Bachmann AS - Search Results

1

Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane.

Zhou XE, Suino-Powell K, Schultz CR, Aleiwi B, Brunzelle JS, Lamp J, Vega IE, Ellsworth E, Bachmann AS, Melcher K. Zhou XE, et al. Among authors: bachmann as. Biochem J. 2021 Dec 10;478(23):4137-4149. doi: 10.1042/BCJ20210647. Biochem J. 2021. PMID: 34796899 Free PMC article.

2

AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport.

Samal K, Zhao P, Kendzicky A, Yco LP, McClung H, Gerner E, Burns M, Bachmann AS, Sholler G. Samal K, et al. Among authors: bachmann as. Int J Cancer. 2013 Sep 15;133(6):1323-33. doi: 10.1002/ijc.28139. Epub 2013 May 30. Int J Cancer. 2013. PMID: 23457004 Free article.

3

Ornithine decarboxylase as a therapeutic target for endometrial cancer.

Kim HI, Schultz CR, Buras AL, Friedman E, Fedorko A, Seamon L, Chandramouli GVR, Maxwell GL, Bachmann AS, Risinger JI. Kim HI, et al. Among authors: bachmann as. PLoS One. 2017 Dec 14;12(12):e0189044. doi: 10.1371/journal.pone.0189044. eCollection 2017. PLoS One. 2017. PMID: 29240775 Free PMC article.

4

Immunoproteasome inhibition and bioactivity of thiasyrbactins.

Bakas NA, Schultz CR, Yco LP, Roberts CC, Chang CA, Bachmann AS, Pirrung MC. Bakas NA, et al. Among authors: bachmann as. Bioorg Med Chem. 2018 Jan 15;26(2):401-412. doi: 10.1016/j.bmc.2017.11.048. Epub 2017 Dec 7. Bioorg Med Chem. 2018. PMID: 29269255 Free PMC article.

5

Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.

Schultz CR, Geerts D, Mooney M, El-Khawaja R, Koster J, Bachmann AS. Schultz CR, et al. Among authors: bachmann as. Biochem J. 2018 Jan 31;475(2):531-545. doi: 10.1042/BCJ20170597. Biochem J. 2018. PMID: 29295892

6

Harmine, a dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor induces caspase-mediated apoptosis in neuroblastoma.

Uhl KL, Schultz CR, Geerts D, Bachmann AS. Uhl KL, et al. Among authors: bachmann as. Cancer Cell Int. 2018 Jun 7;18:82. doi: 10.1186/s12935-018-0574-3. eCollection 2018. Cancer Cell Int. 2018. PMID: 29977157 Free PMC article.

7

Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy.

Weicht RR, Schultz CR, Geerts D, Uhl KL, Bachmann AS. Weicht RR, et al. Among authors: bachmann as. Med Sci (Basel). 2018 Aug 16;6(3):65. doi: 10.3390/medsci6030065. Med Sci (Basel). 2018. PMID: 30115881 Free PMC article.

8

Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features.

Bupp CP, Schultz CR, Uhl KL, Rajasekaran S, Bachmann AS. Bupp CP, et al. Among authors: bachmann as. Am J Med Genet A. 2018 Dec;176(12):2548-2553. doi: 10.1002/ajmg.a.40523. Epub 2018 Sep 21. Am J Med Genet A. 2018. PMID: 30239107

9

Anti-tumor effect of sulfasalazine in neuroblastoma.

Mooney MR, Geerts D, Kort EJ, Bachmann AS. Mooney MR, et al. Among authors: bachmann as. Biochem Pharmacol. 2019 Apr;162:237-249. doi: 10.1016/j.bcp.2019.01.007. Epub 2019 Jan 9. Biochem Pharmacol. 2019. PMID: 30639262

10

Biochemical features of primary cells from a pediatric patient with a gain-of-function ODC1 genetic mutation.

Schultz CR, Bupp CP, Rajasekaran S, Bachmann AS. Schultz CR, et al. Among authors: bachmann as. Biochem J. 2019 Jul 24;476(14):2047-2057. doi: 10.1042/BCJ20190294. Biochem J. 2019. PMID: 31249027

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