Bachmann AS - Search Results

1

Allicin, a Potent New Ornithine Decarboxylase Inhibitor in Neuroblastoma Cells.

Schultz CR, Gruhlke MCH, Slusarenko AJ, Bachmann AS. Schultz CR, et al. Among authors: bachmann as. J Nat Prod. 2020 Aug 28;83(8):2518-2527. doi: 10.1021/acs.jnatprod.0c00613. Epub 2020 Aug 12. J Nat Prod. 2020. PMID: 32786875 Free PMC article.

2

AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport.

Samal K, Zhao P, Kendzicky A, Yco LP, McClung H, Gerner E, Burns M, Bachmann AS, Sholler G. Samal K, et al. Among authors: bachmann as. Int J Cancer. 2013 Sep 15;133(6):1323-33. doi: 10.1002/ijc.28139. Epub 2013 May 30. Int J Cancer. 2013. PMID: 23457004 Free article.

3

A Phase I Trial of DFMO Targeting Polyamine Addiction in Patients with Relapsed/Refractory Neuroblastoma.

Saulnier Sholler GL, Gerner EW, Bergendahl G, MacArthur RB, VanderWerff A, Ashikaga T, Bond JP, Ferguson W, Roberts W, Wada RK, Eslin D, Kraveka JM, Kaplan J, Mitchell D, Parikh NS, Neville K, Sender L, Higgins T, Kawakita M, Hiramatsu K, Moriya SS, Bachmann AS. Saulnier Sholler GL, et al. Among authors: bachmann as. PLoS One. 2015 May 27;10(5):e0127246. doi: 10.1371/journal.pone.0127246. eCollection 2015. PLoS One. 2015. PMID: 26018967 Free PMC article. Clinical Trial.

4

Effect of sulfasalazine on human neuroblastoma: analysis of sepiapterin reductase (SPR) as a new therapeutic target.

Yco LP, Geerts D, Mocz G, Koster J, Bachmann AS. Yco LP, et al. Among authors: bachmann as. BMC Cancer. 2015 Jun 21;15:477. doi: 10.1186/s12885-015-1447-y. BMC Cancer. 2015. PMID: 26093909 Free PMC article.

5

Ornithine decarboxylase as a therapeutic target for endometrial cancer.

Kim HI, Schultz CR, Buras AL, Friedman E, Fedorko A, Seamon L, Chandramouli GVR, Maxwell GL, Bachmann AS, Risinger JI. Kim HI, et al. Among authors: bachmann as. PLoS One. 2017 Dec 14;12(12):e0189044. doi: 10.1371/journal.pone.0189044. eCollection 2017. PLoS One. 2017. PMID: 29240775 Free PMC article.

6

Immunoproteasome inhibition and bioactivity of thiasyrbactins.

Bakas NA, Schultz CR, Yco LP, Roberts CC, Chang CA, Bachmann AS, Pirrung MC. Bakas NA, et al. Among authors: bachmann as. Bioorg Med Chem. 2018 Jan 15;26(2):401-412. doi: 10.1016/j.bmc.2017.11.048. Epub 2017 Dec 7. Bioorg Med Chem. 2018. PMID: 29269255 Free PMC article.

7

Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.

Schultz CR, Geerts D, Mooney M, El-Khawaja R, Koster J, Bachmann AS. Schultz CR, et al. Among authors: bachmann as. Biochem J. 2018 Jan 31;475(2):531-545. doi: 10.1042/BCJ20170597. Biochem J. 2018. PMID: 29295892

8

Harmine, a dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor induces caspase-mediated apoptosis in neuroblastoma.

Uhl KL, Schultz CR, Geerts D, Bachmann AS. Uhl KL, et al. Among authors: bachmann as. Cancer Cell Int. 2018 Jun 7;18:82. doi: 10.1186/s12935-018-0574-3. eCollection 2018. Cancer Cell Int. 2018. PMID: 29977157 Free PMC article.

9

Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy.

Weicht RR, Schultz CR, Geerts D, Uhl KL, Bachmann AS. Weicht RR, et al. Among authors: bachmann as. Med Sci (Basel). 2018 Aug 16;6(3):65. doi: 10.3390/medsci6030065. Med Sci (Basel). 2018. PMID: 30115881 Free PMC article.

10

Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features.

Bupp CP, Schultz CR, Uhl KL, Rajasekaran S, Bachmann AS. Bupp CP, et al. Among authors: bachmann as. Am J Med Genet A. 2018 Dec;176(12):2548-2553. doi: 10.1002/ajmg.a.40523. Epub 2018 Sep 21. Am J Med Genet A. 2018. PMID: 30239107

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