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Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression.
Bachmann A, Bruske E, Krumkamp R, Turner L, Wichers JS, Petter M, Held J, Duffy MF, Sim BKL, Hoffman SL, Kremsner PG, Lell B, Lavstsen T, Frank M, Mordmüller B, Tannich E. Bachmann A, et al. PLoS Pathog. 2019 Jul 11;15(7):e1007906. doi: 10.1371/journal.ppat.1007906. eCollection 2019 Jul. PLoS Pathog. 2019. PMID: 31295334 Free PMC article. Clinical Trial.
Dissecting the Gene Expression, Localization, Membrane Topology, and Function of the Plasmodium falciparum STEVOR Protein Family.
Wichers JS, Scholz JAM, Strauss J, Witt S, Lill A, Ehnold LI, Neupert N, Liffner B, Lühken R, Petter M, Lorenzen S, Wilson DW, Löw C, Lavazec C, Bruchhaus I, Tannich E, Gilberger TW, Bachmann A. Wichers JS, et al. Among authors: bachmann a. mBio. 2019 Jul 30;10(4):e01500-19. doi: 10.1128/mBio.01500-19. mBio. 2019. PMID: 31363031 Free PMC article.
Common virulence gene expression in adult first-time infected malaria patients and severe cases.
Wichers JS, Tonkin-Hill G, Thye T, Krumkamp R, Kreuels B, Strauss J, von Thien H, Scholz JA, Smedegaard Hansson H, Weisel Jensen R, Turner L, Lorenz FR, Schöllhorn A, Bruchhaus I, Tannich E, Fendel R, Otto TD, Lavstsen T, Gilberger TW, Duffy MF, Bachmann A. Wichers JS, et al. Among authors: bachmann a. Elife. 2021 Apr 28;10:e69040. doi: 10.7554/eLife.69040. Elife. 2021. PMID: 33908865 Free PMC article.
The exception that proves the rule: Virulence gene expression at the onset of Plasmodium falciparum blood stage infections.
Wichers-Misterek JS, Krumkamp R, Held J, von Thien H, Wittmann I, Höppner YD, Ruge JM, Moser K, Dara A, Strauss J, Esen M, Fendel R, Sulyok Z, Jeninga MD, Kremsner PG, Sim BKL, Hoffman SL, Duffy MF, Otto TD, Gilberger TW, Silva JC, Mordmüller B, Petter M, Bachmann A. Wichers-Misterek JS, et al. Among authors: bachmann a. PLoS Pathog. 2023 Jun 29;19(6):e1011468. doi: 10.1371/journal.ppat.1011468. eCollection 2023 Jun. PLoS Pathog. 2023. PMID: 37384799 Free PMC article.
A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture.
Andradi-Brown C, Wichers-Misterek JS, von Thien H, Höppner YD, Scholz JAM, Hansson H, Filtenborg Hocke E, Gilberger TW, Duffy MF, Lavstsen T, Baum J, Otto TD, Cunnington AJ, Bachmann A. Andradi-Brown C, et al. Among authors: bachmann a. Elife. 2024 Jan 25;12:RP87726. doi: 10.7554/eLife.87726. Elife. 2024. PMID: 38270586 Free PMC article.
663 results