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Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host.
Salmon D, Vanwalleghem G, Morias Y, Denoeud J, Krumbholz C, Lhommé F, Bachmaier S, Kador M, Gossmann J, Dias FB, De Muylder G, Uzureau P, Magez S, Moser M, De Baetselier P, Van Den Abbeele J, Beschin A, Boshart M, Pays E. Salmon D, et al. Among authors: bachmaier s. Science. 2012 Jul 27;337(6093):463-6. doi: 10.1126/science.1222753. Epub 2012 Jun 14. Science. 2012. PMID: 22700656
Cyclic AMP effectors in African trypanosomes revealed by genome-scale RNA interference library screening for resistance to the phosphodiesterase inhibitor CpdA.
Gould MK, Bachmaier S, Ali JA, Alsford S, Tagoe DN, Munday JC, Schnaufer AC, Horn D, Boshart M, de Koning HP. Gould MK, et al. Among authors: bachmaier s. Antimicrob Agents Chemother. 2013 Oct;57(10):4882-93. doi: 10.1128/AAC.00508-13. Epub 2013 Jul 22. Antimicrob Agents Chemother. 2013. PMID: 23877697 Free PMC article.
Metabolic selection of a homologous recombination-mediated gene loss protects Trypanosoma brucei from ROS production by glycosomal fumarate reductase.
Wargnies M, Plazolles N, Schenk R, Villafraz O, Dupuy JW, Biran M, Bachmaier S, Baudouin H, Clayton C, Boshart M, Bringaud F. Wargnies M, et al. Among authors: bachmaier s. J Biol Chem. 2021 Jan-Jun;296:100548. doi: 10.1016/j.jbc.2021.100548. Epub 2021 Mar 17. J Biol Chem. 2021. PMID: 33741344 Free PMC article.
Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma.
Bachmaier S, Volpato Santos Y, Kramer S, Githure GB, Klöckner T, Pepperl J, Baums C, Schenk R, Schwede F, Genieser HG, Dupuy JW, Forné I, Imhof A, Basquin J, Lorentzen E, Boshart M. Bachmaier S, et al. Nat Commun. 2019 Mar 29;10(1):1421. doi: 10.1038/s41467-019-09338-z. Nat Commun. 2019. PMID: 30926779 Free PMC article.
33 results