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Cell stretching activates an ATM mechano-transduction pathway that remodels cytoskeleton and chromatin.
Bastianello G, Porcella G, Beznoussenko GV, Kidiyoor G, Ascione F, Li Q, Cattaneo A, Matafora V, Disanza A, Quarto M, Mironov AA, Oldani A, Barozzi S, Bachi A, Costanzo V, Scita G, Foiani M. Bastianello G, et al. Among authors: bachi a. Cell Rep. 2023 Dec 26;42(12):113555. doi: 10.1016/j.celrep.2023.113555. Epub 2023 Dec 11. Cell Rep. 2023. PMID: 38088930 Free article.
Triap1 upregulation promotes escape from mitotic-slippage-induced G1 arrest.
Pavani M, Chiroli E, Cancrini C, Gross F, Bonaiuti P, Villa S, Giavazzi F, Matafora V, Bachi A, Fava LL, Lischetti T, Ciliberto A. Pavani M, et al. Among authors: bachi a. Cell Rep. 2023 Mar 28;42(3):112215. doi: 10.1016/j.celrep.2023.112215. Epub 2023 Mar 13. Cell Rep. 2023. PMID: 36917609 Free article.
Clonal cooperation through soluble metabolite exchange facilitates metastatic outgrowth by modulating Allee effect.
Hershey BJ, Barozzi S, Orsenigo F, Pompei S, Iannelli F, Kamrad S, Matafora V, Pisati F, Calabrese L, Fragale G, Salvadori G, Martini E, Totaro MG, Magni S, Guan R, Parazzoli D, Maiuri P, Bachi A, Patil KR, Cosentino Lagomarsino M, Havas KM. Hershey BJ, et al. Among authors: bachi a. Sci Adv. 2023 Sep 15;9(37):eadh4184. doi: 10.1126/sciadv.adh4184. Epub 2023 Sep 15. Sci Adv. 2023. PMID: 37713487 Free PMC article.
SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA.
Germani S, Van Ho AT, Cherubini A, Varone E, Chernorudskiy A, Renna GM, Fumagalli S, Gobbi M, Lucchetti J, Bolis M, Guarrera L, Craparotta I, Rastelli G, Piccoli G, de Napoli C, Nogara L, Poggio E, Brini M, Cattaneo A, Bachi A, Simmen T, Calì T, Quijano-Roy S, Boncompagni S, Blaauw B, Ferreiro A, Zito E. Germani S, et al. Among authors: bachi a. Cell Rep Med. 2024 Mar 19;5(3):101439. doi: 10.1016/j.xcrm.2024.101439. Epub 2024 Feb 22. Cell Rep Med. 2024. PMID: 38402623 Free PMC article.
Acetyl-CoA carboxylase 1 controls a lipid droplet-peroxisome axis and is a vulnerability of endocrine-resistant ER+ breast cancer.
Bacci M, Lorito N, Smiriglia A, Subbiani A, Bonechi F, Comito G, Morriset L, El Botty R, Benelli M, López-Velazco JI, Caffarel MM, Urruticoechea A, Sflomos G, Malorni L, Corsini M, Ippolito L, Giannoni E, Meattini I, Matafora V, Havas K, Bachi A, Chiarugi P, Marangoni E, Morandi A. Bacci M, et al. Among authors: bachi a. Sci Transl Med. 2024 Feb 28;16(736):eadf9874. doi: 10.1126/scitranslmed.adf9874. Epub 2024 Feb 28. Sci Transl Med. 2024. PMID: 38416843
Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression.
Clerici S, Podrini C, Stefanoni D, Distefano G, Cassina L, Steidl ME, Tronci L, Canu T, Chiaravalli M, Spies D, Bell TA 3rd, Costa AS, Esposito A, D'Alessandro A, Frezza C, Bachi A, Boletta A. Clerici S, et al. Among authors: bachi a. EMBO Mol Med. 2024 Apr 29. doi: 10.1038/s44321-024-00071-9. Online ahead of print. EMBO Mol Med. 2024. PMID: 38684863 Free article.
HERV-W upregulation expression in bipolar disorder and schizophrenia: unraveling potential links to systemic immune/inflammation status.
Rangel SC, da Silva MD, Natrielli Filho DG, Santos SN, do Amaral JB, Victor JR, Silva KCN, Tuleta ID, França CN, Shio MT, Neves LM, Bachi ALL, da Silva Nali LH. Rangel SC, et al. Among authors: bachi all. Retrovirology. 2024 Apr 22;21(1):7. doi: 10.1186/s12977-024-00640-3. Retrovirology. 2024. PMID: 38644495 Free PMC article.
Functional analysis of airway remodeling is related with fibrotic mediators in asthmatic children.
Salles-Dias LP, Brandao-Rangel MAR, Cristina-Rosa A, Morais-Felix RT, Oliveira-Freitas S, Oliveira LVF, Moraes-Ferreira R, Bachi ALL, Coutinho ET, Frison CR, Abbasi A, Melamed D, Vieira RP. Salles-Dias LP, et al. Among authors: bachi all. J Asthma. 2024 Apr 19:1-10. doi: 10.1080/02770903.2024.2338862. Online ahead of print. J Asthma. 2024. PMID: 38577973
305 results