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Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD.
de Almeida RM, Clendenon SG, Richards WG, Boedigheimer M, Damore M, Rossetti S, Harris PC, Herbert BS, Xu WM, Wandinger-Ness A, Ward HH, Glazier JA, Bacallao RL. de Almeida RM, et al. Among authors: bacallao rl. Hum Genomics. 2016 Nov 21;10(1):37. doi: 10.1186/s40246-016-0095-x. Hum Genomics. 2016. PMID: 27871310 Free PMC article.
Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling.
Xu C, Rossetti S, Jiang L, Harris PC, Brown-Glaberman U, Wandinger-Ness A, Bacallao R, Alper SL. Xu C, et al. Am J Physiol Renal Physiol. 2007 Mar;292(3):F930-45. doi: 10.1152/ajprenal.00285.2006. Epub 2006 Nov 7. Am J Physiol Renal Physiol. 2007. PMID: 17090781 Free PMC article.
Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cells.
Xu C, Shmukler BE, Nishimura K, Kaczmarek E, Rossetti S, Harris PC, Wandinger-Ness A, Bacallao RL, Alper SL. Xu C, et al. Among authors: bacallao rl. Am J Physiol Renal Physiol. 2009 Jun;296(6):F1464-76. doi: 10.1152/ajprenal.90542.2008. Epub 2009 Feb 25. Am J Physiol Renal Physiol. 2009. PMID: 19244404 Free PMC article.
77 results