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Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer.
Escobar-Hoyos LF, Penson A, Kannan R, Cho H, Pan CH, Singh RK, Apken LH, Hobbs GA, Luo R, Lecomte N, Babu S, Pan FC, Alonso-Curbelo D, Morris JP 4th, Askan G, Grbovic-Huezo O, Ogrodowski P, Bermeo J, Saglimbeni J, Cruz CD, Ho YJ, Lawrence SA, Melchor JP, Goda GA, Bai K, Pastore A, Hogg SJ, Raghavan S, Bailey P, Chang DK, Biankin A, Shroyer KR, Wolpin BM, Aguirre AJ, Ventura A, Taylor B, Der CJ, Dominguez D, Kümmel D, Oeckinghaus A, Lowe SW, Bradley RK, Abdel-Wahab O, Leach SD. Escobar-Hoyos LF, et al. Among authors: babu s. Cancer Cell. 2020 Aug 10;38(2):198-211.e8. doi: 10.1016/j.ccell.2020.05.010. Epub 2020 Jun 18. Cancer Cell. 2020. PMID: 32559497 Free PMC article.
Keratin 17 is a sensitive and specific biomarker of urothelial neoplasia.
Babu S, Mockler DC, Roa-Peña L, Szygalowicz A, Kim NW, Jahanfard S, Gholami SS, Moffitt R, Fitzgerald JP, Escobar-Hoyos LF, Shroyer KR. Babu S, et al. Mod Pathol. 2019 May;32(5):717-724. doi: 10.1038/s41379-018-0177-5. Epub 2018 Nov 15. Mod Pathol. 2019. PMID: 30443013 Free article.
An unbiased high-throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer.
Pan CH, Otsuka Y, Sridharan B, Woo M, Leiton CV, Babu S, Torrente Gonçalves M, Kawalerski RR, K Bai JD, Chang DK, Biankin AV, Scampavia L, Spicer T, Escobar-Hoyos LF, Shroyer KR. Pan CH, et al. Among authors: babu s. Mol Oncol. 2020 Aug;14(8):1800-1816. doi: 10.1002/1878-0261.12743. Epub 2020 Jul 4. Mol Oncol. 2020. PMID: 32533886 Free PMC article.
Keratin 17 modulates the immune topography of pancreatic cancer.
Delgado-Coka LA, Horowitz M, Torrente-Goncalves M, Roa-Peña L, Leiton CV, Hasan M, Babu S, Fassler D, Oentoro J, Karen Bai JD, Petricoin EF, Matrisian LM, Blais EM, Marchenko N, Allard FD, Jiang W, Larson B, Hendifar A, Chen C, Abousamra S, Samaras D, Kurc T, Saltz J, Escobar-Hoyos LF, Shroyer K. Delgado-Coka LA, et al. Among authors: babu s. Res Sq [Preprint]. 2024 Feb 20:rs.3.rs-3886691. doi: 10.21203/rs.3.rs-3886691/v1. Res Sq. 2024. PMID: 38464123 Free PMC article. Preprint.
Keratin 17 is a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma.
Delgado-Coka LA, Roa-Peña L, Babu S, Horowitz M, Petricoin EF 3rd, Matrisian LM, Blais EM, Marchenko N, Allard FD, Akalin A, Jiang W, Larson BK, Hendifar AE, Picozzi VJ, Choi M, Shroyer KR, Escobar-Hoyos LF. Delgado-Coka LA, et al. Among authors: babu s. Am J Clin Pathol. 2024 Apr 20:aqae038. doi: 10.1093/ajcp/aqae038. Online ahead of print. Am J Clin Pathol. 2024. PMID: 38642081
1,650 results