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Common activation mechanism of class A GPCRs.
Zhou Q, Yang D, Wu M, Guo Y, Guo W, Zhong L, Cai X, Dai A, Jang W, Shakhnovich EI, Liu ZJ, Stevens RC, Lambert NA, Babu MM, Wang MW, Zhao S. Zhou Q, et al. Among authors: babu mm. Elife. 2019 Dec 19;8:e50279. doi: 10.7554/eLife.50279. Elife. 2019. PMID: 31855179 Free PMC article.
Universal allosteric mechanism for Gα activation by GPCRs.
Flock T, Ravarani CNJ, Sun D, Venkatakrishnan AJ, Kayikci M, Tate CG, Veprintsev DB, Babu MM. Flock T, et al. Among authors: babu mm. Nature. 2015 Aug 13;524(7564):173-179. doi: 10.1038/nature14663. Epub 2015 Jul 6. Nature. 2015. PMID: 26147082 Free PMC article.
A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection.
Wright SC, Kozielewicz P, Kowalski-Jahn M, Petersen J, Bowin CF, Slodkowicz G, Marti-Solano M, Rodríguez D, Hot B, Okashah N, Strakova K, Valnohova J, Babu MM, Lambert NA, Carlsson J, Schulte G. Wright SC, et al. Among authors: babu mm. Nat Commun. 2019 Feb 8;10(1):667. doi: 10.1038/s41467-019-08630-2. Nat Commun. 2019. PMID: 30737406 Free PMC article.
Molecular signatures of G-protein-coupled receptors.
Venkatakrishnan AJ, Deupi X, Lebon G, Tate CG, Schertler GF, Babu MM. Venkatakrishnan AJ, et al. Among authors: babu mm. Nature. 2013 Feb 14;494(7436):185-94. doi: 10.1038/nature11896. Nature. 2013. PMID: 23407534 Review.
Selectivity determinants of GPCR-G-protein binding.
Flock T, Hauser AS, Lund N, Gloriam DE, Balaji S, Babu MM. Flock T, et al. Among authors: babu mm. Nature. 2017 May 18;545(7654):317-322. doi: 10.1038/nature22070. Epub 2017 May 10. Nature. 2017. PMID: 28489817 Free PMC article.
188 results